nature.com

Sitemap

  • Log In
  • Register

nature.com blogs

blogs by NPG staff

Advanced search
  • Nature.com Blogs
  • Blog
  • Archive by Tag

Archive by tag | method development

Newer entriesOlder entries

03 Nov 2017 | 17:40 GMT

A conversation about neuroscience

Posted by Vivien Marx | Categories: Neuroscience, This and That

A conversation about neuroscience

Nature research journal editors speak with Eric Nestler and Robert Greene about neurobiology and the Society for Neuroscience (SfN) 2017 annual meeting.  Read more

Tags:

  • brain
  • method development
  • nature communications
  • nature methods
  • Nature Neuroscience
  • neurobiology
  • neuroscience

Article tools

  • Email
  • Share/bookmark

    • Facebook
    • Twitter
    • Delicious
    • Digg
    • Google+
    • LinkedIn
    • Reddit
    • StumbleUpon

05 Oct 2017 | 11:14 BST

A celebration of cryo-EM

Posted by Allison Doerr | Categories: Chemistry, General interest, Structural Biology

Here at Nature Methods, we were quite excited yesterday to wake up to the news that the Nobel Prize in Chemistry had been awarded to Jacques Dubochet, Joachim Frank, and Richard Henderson for their seminal developments in cryo-electron microscopy (better known as cryo-EM) which now enable high-resolution biomolecule structure determination. This is a technique we have been watching closely since 2013, when the first papers (including one of our own) realizing the capability of near-atomic-resolution structure determination with cryo-EM were published.  Read more

Tags:

  • Chemistry
  • method development
  • Nobel Prize
  • proteins

Article tools

  • Email
  • Share/bookmark

    • Facebook
    • Twitter
    • Delicious
    • Digg
    • Google+
    • LinkedIn
    • Reddit
    • StumbleUpon

12 Dec 2016 | 11:39 GMT

Building OpenSPIM systems

Posted by Vivien Marx | Categories: General interest

Building OpenSPIM systems

Tuning reagents, software, or equipment is all in a day’s work in the lab. Building instruments from scratch, however, is a task more typical for physicists who might 3D print or machine the parts they need and then assemble them into the instrument they want. They might construct an instrument for a specific experiment or develop a design that helps hundreds of labs. That model could go on to be modified and hacked in a variety of ways.  Read more

Tags:

  • light-sheet microscopy
  • method development
  • Open-source hardware
  • Open-SPIM

Article tools

  • Email
  • Share/bookmark

    • Facebook
    • Twitter
    • Delicious
    • Digg
    • Google+
    • LinkedIn
    • Reddit
    • StumbleUpon

28 Mar 2013 | 12:55 GMT

Technology development at the heart of ‘big neuroscience’

Posted by erika pastrana | Categories: Editorials, General interest, Neuroscience

European and US initiatives aiming to advance our understanding of brain function depend on new technologies.    … Read more

Tags:

  • method development
  • technology

Article tools

  • add a comment
  • Email
  • Share/bookmark

    • Facebook
    • Twitter
    • Delicious
    • Digg
    • Google+
    • LinkedIn
    • Reddit
    • StumbleUpon

28 Feb 2012 | 17:05 GMT

The potential and perils of trying new methods

Posted by Daniel Evanko | Categories: Editorials, Journal policy

The remit of Nature Methods has always been to publish new or improved methods that will have an immediate practical impact on researchers working at the bench. But unfortunately, ‘new’ methods aren’t always ready for primetime, and the more novel the method the more likely it is that all the kinks aren’t yet worked out.  Read more

Tags:

  • method development

Article tools

  • add a comment
  • Email
  • Share/bookmark

    • Facebook
    • Twitter
    • Delicious
    • Digg
    • Google+
    • LinkedIn
    • Reddit
    • StumbleUpon

30 Jan 2012 | 17:54 GMT

Head-to-head comparisons of methods and tools

Posted by erika pastrana | Categories: Editorials

Choosing the best tool or method for a particular experiment can be a daunting task. Finding the right choice can mean much time and many resources and an improper one can lead to poor or inaccurate results.  Read more

Tags:

  • analysis
  • method development
  • optogenetics
  • super-resolution

Article tools

  • add a comment
  • Email
  • Share/bookmark

    • Facebook
    • Twitter
    • Delicious
    • Digg
    • Google+
    • LinkedIn
    • Reddit
    • StumbleUpon

28 Oct 2011 | 11:00 BST

Where’s your ground truth?

Posted by Daniel Evanko | Categories: Computational, Editorials, Microscopy & Imaging

When using or developing experimental and observational methods it is crucial to assess the method performance in an effort to ensure that the information it provides reflects reality. For experimental biologists this often means conducting carefully chosen control experiments with alternative methods or different experimental settings. More rigorous assessment, particularly for high-throughput or large-scale methods, often requires the use of ‘ground truth’ or ‘gold standard’ data sets. But talk to different people and you will get different answers regarding what ‘ground truth’ or ‘gold standard’ data is. This often includes a nice historical explanation of where the term ‘ground truth’ comes from.  Read more

Tags:

  • analysis
  • data
  • method development
  • software

Article tools

  • add a comment
  • Email
  • Share/bookmark

    • Facebook
    • Twitter
    • Delicious
    • Digg
    • Google+
    • LinkedIn
    • Reddit
    • StumbleUpon

29 Sep 2011 | 11:00 BST

Academic inventions

Posted by Daniel Evanko | Categories: Editorials, General interest

Over the past 30 years the ties between academic research and commercial enterprise have increased enormously. Much of this increase has involved attempts by universities to capitalize on the intellectual property created by their research scientists using the US patent system. The Editorial in the October issue of Nature Methods discusses this change and the challenges facing academics interested in commercializing their innovations.  Read more

Tags:

  • commercialization
  • law
  • method development
  • Obama
  • patents

Article tools

  • add a comment
  • Email
  • Share/bookmark

    • Facebook
    • Twitter
    • Delicious
    • Digg
    • Google+
    • LinkedIn
    • Reddit
    • StumbleUpon

31 Aug 2011 | 14:01 BST

Building a better mouse test

Posted by Allison Doerr | Categories: Editorials, Model Organisms

September’s Editorial praises the new research that more genetic rodent models will enable. However, manipulating important genes in a mouse is not enough. Experimental techniques are also needed. Perhaps nowhere is this more important—and more difficult—than using animals to assess neuropsychiatric diseases. While much can be learned on the level of brain and cell physiology, behavioral tests are important to assess which aspects of physiology are most likely to matter. It’s the behavioral symptoms, not the cell-based ones, that directly affect people’s lives. How useful would a drug be if it cleared away the telltale plaques of Alzheimer’s patients but did nothing to preserve their memories?  Read more

Tags:

  • animal models
  • method development
  • mouse
  • neuroscience

Article tools

  • add a comment
  • Email
  • Share/bookmark

    • Facebook
    • Twitter
    • Delicious
    • Digg
    • Google+
    • LinkedIn
    • Reddit
    • StumbleUpon

28 Apr 2011 | 12:00 BST

Efficiency through analysis

Posted by Daniel Evanko | Categories: Editorials, Nature Methods papers

The May Editorial in Nature Methods discusses how the overall efficiency of research can be improved by comparative analysis of research method and tool performance.  Read more

Tags:

  • analysis
  • method development

Article tools

  • add a comment
  • Email
  • Share/bookmark

    • Facebook
    • Twitter
    • Delicious
    • Digg
    • Google+
    • LinkedIn
    • Reddit
    • StumbleUpon
Newer entriesOlder entries

About this blog

nature.com blogs
  • E-alert
  • RSS
nature.com blogs home

Search

Categories

  • #NJCE14
  • #NJCEBoston
  • #NJCELondon
  • #NJCESanFrancisco
  • #ScientistOnTheMove
  • – Blessed Okole
  • – Brady Huggett
  • – Bruce Booth
  • – Chris Dippel
  • – Chris Hillier
  • – David Wilson
  • – Ed Rybicki
  • – Fahd Al-Mulla
  • – Fernando Kreutz
  • – James Taylor
  • – Janette Dixon
  • – John McCulloch
  • – Julio Vito Wykrota
  • – Karen Liu
  • – Luiz Antonio Barreto deCastro
  • – Martin Partl
  • – Matthew Chervenak
  • – Michael Francisco
  • – Pramod Yadava
  • – Prashanth Bagali
  • – Samuel JK Abraham
  • – Viren Konde
  • 2012
  • About this blog
  • Academia
  • Academics
  • Access
  • Acoustics
  • Adaptation
  • Admin
  • Advertorial
  • Agriculture
  • AIDS
  • Alicia Newton
  • American Association for Cancer Research
  • American Association for the Advancement of Science
  • American Association of Physical Anthropology
  • American Astronomical Society
  • American Geophysical Union
  • American Physical Society
  • American Society for Cell Biology
  • American Society for Reproductive Medicine
  • American Society of Human Genetics
  • American Society of Microbiology
  • Andrew Mitchinson
  • Animal Behavior Society
  • Animal experiments
  • Anna Barnett
  • Anne Pichon
  • Antarctic field research 2010
  • Anthropolgy
  • Anthropology
  • Apiculture
  • Arboriculture
  • Archaeology
  • Archaeology and anthropology
  • Art of Science
  • Artificial intelligence
  • Arts
  • Ask the expert
  • Astronomy & astrophysics
  • Astrophysics
  • Author benefits
  • Author services
  • Author Services Feedback
  • Author's Corner
  • Authorship
  • Award
  • Awards
  • Awards and prizes
  • Away from home
  • Barcelona climate change conference
  • Behind the paper
  • Bio-imaging
  • Bioinformatics
  • Biological_approaches
  • Biology & Biotechnology
  • Biology and biotechnology
  • Biophysics
  • Biosecurity
  • Biotechnology
  • Blog
  • Blog Information
  • Blogging
  • Blogroll
  • Blogroll
  • books
  • Books & Arts
  • Boston Astronomy
  • Boston biotech
  • Boston Research
  • Boston science
  • Breaking News
  • Browser tabs
  • Burgess Shale Centenary
  • Business
  • Business development
  • Calls for Submissions
  • Canadian icebreaker
  • Cancer biology
  • Carbon markets
  • Career paths
  • Careers
  • Careers articles
  • Cartography
  • Categories
  • Celebrating the Day of Light
  • Cell and molecular biology
  • Cell Biology
  • Chemistry
  • Chemistry
  • Chemistry in retrospect
  • Citation analysis
  • Climate Change
  • Climate Policy
  • Climate prediction
  • Collaboration
  • Communication
  • Communities Happenings
  • Community
  • Competing interests
  • Competition
  • Computational
  • Computational approaches
  • Computational_approaches
  • Computer science
  • Conference Highlights
  • Conference reports
  • Conferences
  • Conservation science
  • COP18
  • COVID19
  • Cryosphere
  • CV
  • Daily Dose
  • Data availability
  • Data integration
  • Data Matters
  • Data policy
  • Data Reuse
  • Design
  • Development
  • Diabetes and metabolism
  • Digital Science
  • Disciplines
  • Diversity
  • Drug discovery
  • Drugs, drugs and more drugs
  • Durban climate summit
  • Earth and environment
  • Earth System Science Partnership
  • Earth, environment & ecology
  • Ebola
  • Ecological Society of America
  • Ecology
  • Ecology and Evolution
  • Editor Posts
  • Editorials
  • Education
  • Elisa De Ranieri
  • Energy
  • Entomology
  • Entrepreneurship
  • Environment
  • Environmental sciences
  • Ethical / Social
  • Ethics
  • Europe
  • European Society of Human Reproduction & Embryology
  • Euroscience Open Forum
  • Events
  • Everest expedition
  • Evolution
  • Evolution and paleontology
  • Expeditions
  • Faculty
  • Featured
  • Feedback
  • Film
  • Films
  • Finance
  • Financial Crisis
  • First Rounders
  • Five Day Filter
  • food science
  • Format
  • Forum
  • Fukushima
  • Funding
  • funding
  • Gavin Armstrong
  • Gene expression
  • Gene function
  • Gene regulation
  • General
  • General interest
  • Genetic association
  • Genetics
  • Genetics & Genomics
  • Genome-wide
  • Geological Society of America
  • Geoscience
  • Giulia Pacchioni
  • Global issues
  • Global Seed Vault opening
  • Grants, tenure and positions
  • Graphene Week
  • Guest blog posts
  • Guest features
  • Guest Post
  • Health
  • Health and medicine
  • Hints and Wrinkles
  • History of genetics
  • History of science
  • HIV/AIDS
  • How to answer
  • I-han Chou
  • Immunology
  • Import
  • In the Field
  • In the News
  • In your element
  • Industry
  • Infectious diseases
  • Institutions
  • Interactions
  • Interdisciplinarity
  • International AIDS conference
  • International Astronomical Union
  • International Relations
  • International Society for Stem Cell Research
  • Internship
  • IP/ Tech Transfer
  • Journal happenings
  • Journal journeys
  • Journal policy
  • Lab life
  • Lab story
  • Lepton Photon
  • Libraries
  • Liesbeth Venema
  • Lindau lessons
  • Lindau Nobel Laureate Meetings (lnlm)
  • Linkage
  • Local news
  • Luigi Martiradonna
  • Lunar and Planetary Science
  • Malaria
  • Marine science
  • Mass spectrometry
  • Materials Girl
  • Materials science
  • Medical research
  • Medical science
  • Meet the editor
  • Meeting report
  • Meetings
  • Mentoring
  • Mentoring and training
  • Metadata
  • Metagenomics
  • Method of the year
  • Microbiology
  • Microscopy & Imaging
  • Military science
  • Misconduct
  • MIT
  • Mitigation
  • Mobility
  • Model Organisms
  • Modeling
  • Molecular gastronomy
  • Monthly Map
  • Move
  • MSB updates
  • Multi-scale
  • Multimedia
  • My science failures
  • Nano-engineering
  • Nanotechnology
  • NASA Phoenix Landing
  • Nascent
  • Natural disasters
  • Natural history
  • Nature Covers
  • Nature Genetics Anniversary
  • Nature Genetics covers
  • Nature Genetics standards
  • Nature Graphics
  • Nature India Annual Volume
  • Nature India Essay Competition
  • Nature India photo contest
  • Nature India Photo Story
  • Nature India Special Issue
  • Nature Methods papers
  • Nature Nanotechnology
  • Nature Network round-up
  • Nature Research
  • nature.com blogs
  • nature.com blogs info
  • NChem research highlights
  • Neil Withers
  • Networks
  • Neuroscience
  • Neuroscience/mental health
  • New in Nature
  • New tools and techniques
  • news
  • News and Events
  • News and Updates
  • NJCE15
  • NJCEDusseldorf
  • Noah Gray
  • NPG special content
  • Obituary
  • Odds and ends
  • Oil spill science
  • Olive Heffernan
  • Oliver Morton
  • On Nature News
  • On the road
  • Open access
  • Open acess
  • Open peer review
  • Ornithology
  • Other authors
  • Other columns
  • Other Contributors
  • Palaeoclimate
  • Palaeontology
  • Paleontology
  • Particle Physics
  • Partnering / Licensing
  • Partners
  • Peer review debate
  • Peer Review Feedback
  • Peer review trial
  • people
  • People Management
  • Perspectives
  • Philosophy or Psychology or Ethics
  • Physics
  • Physics & Mathematics
  • Physics at the interface
  • Physiology
  • Picks of the week
  • Planetary science
  • Planetary sciences
  • Plant biology
  • Plant sciences
  • Podcasts
  • Policies
  • Policies Feedback
  • Policy
  • Policy and Public
  • Politics
  • Pollution
  • Postdoc
  • Postgraduate
  • Poznan climate-change conference
  • Pre-publicity
  • Press Release
  • Print
  • Proteomics
  • Protocols methods recipes cookery
  • Public and media
  • Publications
  • Publishing
  • Publishing tips
  • Quality and value
  • Quality measures
  • Quantitative
  • Quotes of the day
  • Random Thoughts
  • Rare diseases
  • Reactions
  • Regional Initiatives
  • Regulatory
  • Relationships
  • Report
  • Reports
  • Repository Highlights
  • Research
  • Research findings
  • Research Highlights
  • Resources
  • RNAi
  • Road to Copenhagen
  • Roberta Kwok
  • Robotics
  • Roundup
  • Royal Institution
  • Schedules
  • Scholarly impact
  • SciArt scribbles
  • Science
  • Science administration
  • Science around the world
  • Science calendars
  • Science Communication
  • Science communication and outreach
  • Science education
  • science events
  • Science festivals
  • Science film
  • Science Journalism
  • Science maps
  • science news
  • Science Online Bay Area (SoBA)
  • Science Online London (SoLo)
  • Science Online NYC
  • Science Online NYC (SoNYC)
  • Science Online Seattle (SoSEA)
  • Science Online Vancouver (SoVan)
  • Science organisations
  • Sciences
  • Scientific American
  • Scientific publishing
  • Scientific Reports
  • Scientists on the move
  • Sequencing
  • SfN Meeting
  • Silvia Milana
  • Single molecule
  • Site Updates
  • Soapbox Science Info
  • Social media
  • Social sciences
  • Social software
  • Society
  • Society for American Archaeology
  • Society for Developmental Biology
  • Society for Neuroscience
  • Society for the Study of Reproduction
  • SoNYC
  • Space
  • Space and astronomy
  • Spotlights
  • Springer Nature
  • SpringerMaterials
  • Starting the LHC
  • STEM
  • stem cells
  • Stem cells/cloning
  • Stephen Davey
  • Structural Biology
  • Structural Genomics
  • Stuart Cantrill
  • Support
  • Swine flu
  • Synthetic
  • Synthetic Biology
  • Systems
  • Systems Medicine
  • Technical solutions
  • Technology
  • Technology
  • Technology
  • Tenure
  • The News Net
  • There and Back Again
  • This and That
  • Tools and Techniques
  • Transcriptomics
  • Tuberculosis
  • UK
  • Uncategorized
  • Undergraduate
  • Unemployment
  • Union
  • US
  • Video
  • video and podcasts
  • Virology
  • Visualization
  • WCC-3
  • Webcast
  • Webcasts
  • Weekly round-up
  • Weekly Update
  • What's New in Nature Neuroscience
  • Wildlife
  • Wisdom
  • Women's world
  • World Conference of Science Journalists
  • World Science Festival
  • World watch
  • Writing

All nature.com blogs

  • A view From the BridgeA view From the Bridge
  • Action PotentialAction Potential
  • Flat Chat Flat Chat
  • Free AssociationFree Association
  • House of WisdomHouse of Wisdom
  • IndigenusIndigenus
  • MethagoraMethagora
  • Nature Future ConditionalNature Future Conditional
  • nature.com blogsnature.com blogs
  • Naturejobs BlogNaturejobs Blog
  • Of Schemes and Memes BlogOf Schemes and Memes Blog
  • On your wavelengthOn your wavelength
  • Plant LifePlant Life
  • Scientific DataScientific Data
  • Soapbox ScienceSoapbox Science
  • Spoonful of MedicineSpoonful of Medicine
  • StepwiseStepwise
  • The Sceptical ChymistThe Sceptical Chymist
  • Trade SecretsTrade Secrets
  • About us
  • Contact us
  • Accessibility statement
  • Help
  • Privacy policy
  • Use of cookies
  • Legal notice
  • Terms
  • Nature jobs
  • Nature Asia
  • Nature Education
  • RSS web feeds
Advanced search

© 2021 Springer Nature Limited. All Rights Reserved. partner of AGORA, HINARI, OARE, INASP, ORCID, CrossRef and COUNTER