Nature Genetics | Free Association

Adventures in personal genomicsland


I recall a joke that probably plenty of folks have told; I heard it

from Francis Collins, the head of NIH’s Genome Project.

A previously-married woman heads to bed for the first time with her

new beau, and to his surprise, she admits to being a virgin. When he

wonders why, she says, “Well, I was married to a genome biologist, and

every night, he just sat in bed and talked about how great our sex

life would be someday.”

The Genetic Genealogist

myDNAchoice – Are Your Surfing Habits the Result of Your Genome?

The Gene Sherpa

One of these companies will get sued

The Personal Genome

For example, I share parts of my Y-chromosome with my father (I didn’t

ask his permission to post parts of it online it either).


Googling around, I found that the APOE gene on chromosome 19 is of

particular interest, specifically APOE e2, e3 and e4. In the Genome

Explorer, I can type in APOE, and it takes me to a listing of 19 SNPs

on the APOE gene. Ok, great. But I have no idea which one(s) of those

SNPs are the ones we’re talking about and what the mutations are.

Without this last bit, the Genome Explorer is basically meaningless.


  1. Report this comment

    Vectorpedia(Rick) said:

    I enjoyed the joke by Francis Collins but I would suggest the previously-married womans husband who was a genome biologist may have also had a secret life as a futurist……..a man of dreams and no action……LOL