In The Field

AACR 2010: The BATTLE wages on

Today there was a lot of buzz surrounding the release of results from the BATTLE trial (Biomarker-integrated Approaches of Targeted Therapy for Lung cancer Elimination), sponsored by the US Department of Defense. This trial, started in 2006 attempted to group patients by predominant biologic features of their cancer, including those that can be characterized by genetic changes in EGFR, KRas, RXR/CyclinD1 or VEGF (all predominant defining molecular signatures lung cancer) and see if they could match these patients with the optimal treatments choosing from four treatment regimens. 

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