In The Field

AACR 2010: The Thermos approach to cancer biology

More research presented today at AACR’s 101st annual meeting shed some light on the mind blowing complexity of cancer. At this morning’s plenary sessions, Alan Balmain of the University of California San Francisco showed how the simple model of cancer initiation leading to progression and metastasis was a vast oversimplification. Cancer cells, he says require help from otherwise normal stromal cells, blood vessels, and inflammatory cells. And while much of the research presented at this meeting has been about cataloguing mutations that are gained in cancer, he’s been trying to better understand the underlying genetic background that plays a role in intrinsic susceptibility to cancers. 

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