Archive by category | Proteomics

Computable sugars: some computational resources in glycoscience

Glycoscience is sweet science

As glycoscience advances, labs will increasingly want to ask questions about glycosylation sites on a protein or the structure of a sugar, says Raja Mazumder, a bioinformatician at George Washington University. They might ask for example: are there glycosyltransferases that are expressed in liver but not in the heart, or, which ones are overexpressed by a factor of three in more than two cancers. Such questions require infrastructure building, he says, because right now there is no mechanism to allow such queries. But he and others are building such capabilities. Mazumder along with William York at the University of Georgia are starting to build a glycoscience informatics portal.  Read more

Proteomics data deposition to public repositories

Starting in March, Nature Methods strongly recommends deposition of proteomics data to public repositories before manuscript submission. An Editorial in the March issue describes the motivation of this decision and comments on the public repositories that are now available to proteomics researchers.  Read more