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Good paper journal club: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs

This is a paper under discussion at the Nature Network forum for good, clearly written papers.

Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs

by J R Vane

Nature New Biology 231, 232-235 (1971). Download PDF

Experiments with guinea-pig lung suggest that some of the therapeutic effects of sodium salicylate and aspirin-like drugs are due to inhibition of the synthesis of prostaglandins.

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