Nautilus

Nature’s Insight on quantitative genetics

Nature’s latest Insight collection of reviews (Nature 456, 719–744; 2008) is on the topic of quantitative genetics. Recent revolutions in genomic technologies have led to a renewed interest in quantitative genetics. One of the main areas of study is the genetic basis of complex traits, which proved difficult to investigate until the advent of genome-wide association studies. Findings from a wide variety of organisms — from plants to mice to humans — are now markedly improving our understanding of how genotype contributes to phenotype. Two articles from this Insight are free to access online for one month from date of publication (11 December 2008):

Commentary: A global network for investigating the genomic epidemiology of malaria

The Malaria Genomic Epidemiology Network

Review: Reverse engineering the genotype–phenotype map with natural genetic variation

Matthew V. Rockman.

Futher information about the field of quantitative genetics can be found in the introductory article of this Insight (also free to access online) by Chris Gunter.

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