The Middle and The End at The EMBO Journal

‘The Middle & The End’ is an EMBO Journal review series of free- or open-access articles focusing on different facets of centromere and telomere biology. The specialization of centromeres and telomeres, the middle and end regions of eukaryotic chromosomes, respectively, is reflected at numerous levels, such as chromatin, gene regulation, signalling or cellular function. Nine review articles, combined in this web focus The Middle & The End, and published in print over several issues of The EMBO Journal, summarize current understanding of these aspects of chromosome biology, especially in the light of recent advances, demonstrating parallels as well as differences in the function and organization of centres and ends.

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