On Monday 8 June, Nature is hosting The Big Science Debate: A Biological Century? The event starts at 7 p.m. at Kings Place 90 York Way, London NI. Physics, biology and chemistry have all helped define the twentieth century. Many world-changing innovations from physics include electric power, the microchip and the internal combustion engine. In biology and chemistry, an agricultural revolution has helped to feed a growing population. But some of these advances have also helped to create climate change and a rate of species-loss not seen since the last mass extinction. What will physics and biology look like 50 years from now? And what might the impacts be?