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RNA treatment kills mice

Using RNA interference to shut down harmful genes can have fatal flaw.

New studies on the safety of a gene-silencing mechanism highlight the need for caution before clinical trials, scientists say.

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In fact this research output is a very vital one. It has thrown light on the need for a very careful and comprahensive approach to use RNAi in animal or plant functional geomics. I am more concerned with use of this on crops where less is known on genome sequence thereby the BLAST wont predict misdirected silencing.

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