« Planets are round | Main | Nature Podcast 17Aug »

AIDS: The superiority of old guys

Erika, you are so inefficient. You had to interview two people to get pro and con views on the likelihood of an HIV vaccine. I got both sides from one person, Dr. Peggy Johnston, Director of the Vaccine and Prevention Research Program at NIAID. I asked her whether it was possible that we might never have a vaccine. “Yes, that’s possible,” she said. But she was also optimistic that the vaccine campaign would succeed.

Johnston's explanations left me with the conclusion that this is the most difficult vaccine challenge in history, partly because of the evasive behavior of the virus (as you said) and partly because no one knows the proper balance of humoral and cell-mediated immunity to stimulate. Or how to stimulate it. That’s when I asked her about the possibility of – wait for it – failure.

I’m not just writing this to demonstrate the superiority of old guys (though that’s always fun), but to make a point. No one knows whether there will ever be an HIV vaccine. Anyone who says otherwise is either ignorant or dishonest. Or an administrator. They get a pass on reality.

TrackBack

TrackBack URL for this entry:
http://blogs.nature.com/cgi-bin/mt/mt-tb.cgi/1012

Comments

It is true, if the scientists were able to discover a vaccine, they would have done it 25 years ago. probably they are finding it difficult to understand the behavoir of the virus. But once they are sure, then there is no looking back. But the queston is when are they going to identify that wierd behavior of the virus..............

Post a comment

Comments will be reviewed by staff before being published. You can be as critical or controversial as you like, but please don't get personal or offensive, and do keep it brief. Excessively long entries may be cropped. Remember this is for feedback and discussion - not for publishing papers or press releases.

We strongly encourage you to use your real, full name. Email addresses are required: this is just in case we need to discuss your comment with you privately. They won’t be published.


Please enter the numbers you see below - this helps us to cut down on spam. Note that attempting to post within 30 seconds of hitting ‘preview’ or ‘post’ can cause the system to think you are spamming the site. If you are having trouble with this system, you can instead e-mail a comment to 'inthefield at nature.com'.