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Light shed on battle against HIV

Simple strategy may give tired T cells a boost.

Why does the human body fail to defend itself from the virus that causes AIDS? The answer, researchers are finding, could be that HIV triggers a natural mechanism that impairs the main cells responsible for fighting the virus.

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Posted by Nicola Jones on August 22, 2006 02:23 PM |

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Intense persuasion, triggering the innate immune system to initiate the adaptive immune system. A chronic immune response maybe interpreted as weak metabolic signaling. The involved dendrite cells, T cells and macrophages have not been provoked beyond tolerance. Using nicotinic acid to overexpress PPAR will cause unfurling of its' complement genes. This will shift dendrite cells towards MHC release, T-cells, increase TNF and macrophages phagocytotis. Improved functions of PPAR will facilitate the ubiquitin-proteasome system, and other pathways. The enhanced metabolic signals will provoke the adaptive immune system to differentiate lymphocytes to memory B cell and memory T cells that have complete compliment genes activation. Now under a robust immune response, any chronic infection that has establishes suboptimal activation of dendritic cells, memory B cells and macrophages can be eradicated.

SIncerely,

Norman A. Smith

Posted by: Norman A. Smith | February 29, 2008 02:22 AM

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