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Promising signs emerging from HIV gene therapy trials

Although primarily designed to assess safety and feasibility of the treatment developed by Sangamo BioSciences, the Phase I trials, coupled with results from other basic and animal studies, have several AIDS experts talking tentatively about the possibility of a cure for the disease, something that scientists and clinicians have avoided since disappointments in the mid 1990s. “Cure has been a four letter word,” says Steven Deeks a clinical researcher at the University of California San Francisco, who has patients enrolled in one of the trials.

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