What's in a name?
Checking the literature in preparation for our monthly News & Views meeting, my colleague Clare Thomas spotted this recent paper from PLoS Pathogens:
HMBA Releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and Activates HIV Transcription
No offense intended to the authors or the editors, but I think it's safe to say that there's one too many abbreviations in the title.
Can anyone out there trump it?

Comments
I understand your point something from an unknown area to me with so many acronyms would make me laugh for sure.
At the same time if we write "Hexamethylene bisacetamide releases positive transcription elongation factor b from hexamethylene bisacetamide inducible protein 1 and 7SK small nuclear ribonuclic acid via phosphatidyl inositol 3 kinase / Akt and activates human immunodeficiency virus transcription "
I think nobody else could yet understand right? And there are limits for the number of characters in scientific publication titles which can not be written in "lay language". In addition, such speciic research will be read by people in the HIV or transcription field of research and acronyms are explained in the text of the publication.
(Sorry but Akt has to remain like this it has no real useful meaning by itself although I could call it also protein kinase B.)
The comment by Massimo Sandal makes sense to me as well...
But thanks for pointing it out, it actually made some publicity for the paper ;-)
Posted by: xavier contreras | January 23, 2008 03:09 PM
I understand the title of that paper is funny, and made me smile too, however: what's actually wrong with that title?
Those abbreviations are nothing less, nothing more than names of objects. Just like "human" and "electron". The words that in our language indicate these objects are these abbreviations, so we have to use them. Is there a different way to deal with them?
Posted by: Massimo Sandal | October 26, 2007 09:18 AM
Actually, I think the phrase needs some more abbreviations. It should read something like:
"HMBA Rlses P-TEFb frm HEXIM1 & 7SK snRNA via PI3K/Akt & Actvts HIV Trnscrptn"
Hmmm... no, still too long. But it's a great idea to implement TOC alerts for mobile phones, using text messages...
Posted by: Cesar Sanchez | October 22, 2007 07:38 AM
I certainly can not trump that. However, I thank you for a good laugh. The most embarrassing thing for me is that I nearly understand it...
By the way, the hmba comment above is pure zombie spam. I've received it on my blog, too. I suppose it got attracted here by the first acronym in the title you cite.
Posted by: Alethea | October 21, 2007 04:20 PM
thanks for this reply, but how is it relevant to the question above?
JCL
Posted by: JCL | October 18, 2007 06:29 AM
The most lethal property of cancer cells is that they grow and spread from one location in the body to another. The cancer cell spreading is called metastasis. What makes cancer cells grow and why do cancer cells spread? Robert Weinberg and friends have spent a lifetime askingthat question. It's the one million dollar question. People who unlock the secrets of cancer growth and metastasis( cancer cells spreading from one area to another) will have solved the greatest mystery in medicine and saved millions of lives.
Posted by: hmba | October 18, 2007 02:13 AM