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Highlights of recent methods papers

Each month, the editorial team gets together to select papers describing exciting new methods to cover in short news pieces in the Research Highlights section of the journal. We comb the recent literature in top general journals like Nature, Science and Cell, as well as top specialized journals in various subject areas, and we even take suggestions from authors! Unfortunately, we cannot cover all of the interesting methods papers we find, so each month I will highlight these papers, which didn't quite make the cut, in Methagora.

Here are a few such papers describing intriguing methods, which were published within the last month or so. Enjoy!

Imaging intracellular viscosity of a single cell during photoinduced cell death
Nature Chemistry 1, 69 - 73 (2009)

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
Nature Biotechnology 27, 275 - 280 (2009)

The Dynamic Control of Kiss-And-Run and Vesicular Reuse Probed with Single Nanoparticles
Science 323, 1448 - 1453 (2009)

Identifying the proteins to which small-molecule probes and drugs bind in cells
PNAS
106, 4617 - 4622 (2009)

Femtosecond characterization of vibrational optical activity of chiral molecules
Nature 458, 310 - 313 (2009)

A membrane interferometer
PNAS, published online March 23, 2009

Biodegradable luminescent porous silicon nanoparticles for in vivo applications
Nature Materials 8, 331 - 336 (2009)

Identification and quantitation of newly synthesized proteins in E. coli by enrichment of azido homoalanine-labeled peptides with diagonal chromatography
Mol. Cell. Proteomics
, published online March 25, 2009

STED microscopy reveals crystal colour centres with nanometric resolution
Nature Photonics 3, 144 - 147 (2009)

Comments

Surprisingly, all papers, describing exciting new methods to cover in short news pieces, are TECHNICAL in origin. I mean that articles results, one may read in the best peer-reviewes all around the world, are gathered with sophisticated semeiotics, overlooking other original, interesting and useful papers, as usually rejected by Nature, Science and Cell,e.g., BUT published fortunately either on these "websites" or in other websites, whose Editors are farsighted and open-minded: See, for instance, http://sciphu.com/, recomended by www.nature.com (http://blogs.nature.com/blogs/atoz/S). I invite you kindly to meditate on my words.

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