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Lai et al.

Dynorphin A activates bradykinin receptors to maintain neuropathic pain

Opioids usually alleviate pain by acting at opiate receptors, but this study now reports that the opioid dynorphin A can also activate bradykinin receptors, thereby contributing to neuropathic pain.

Posted by Annette Markus at 02:42 PM on December 03, 2006 | | Comments (1) | TrackBacks (0)
Categories: Annette Markus

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Very interesting! Some kind of 'gating' or a 'permissive' pathway may be behind this. Curiously, drugs curing fever (aspirin) cause fever (pyrexia) themselves and antimalignancy compounds are themselves carcinogenic.

Posted by: Amiya Sarkar | November 26, 2008 01:19 PM

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