The Seven Stones

Glia-neuron interactions

Nature Neuroscience has a nice special focus on glia and disease. The featured reviews and perspective articles discuss multiple aspects of neuron-glia interactions and their role in disease. The reason why I am highlighting this collection here is that I have the feeling that this field could potentially be a nice playground for systems biology. For example, Rossi and colleagues (2007) review the various metabolic processes affected during brain ischemia. Several of the examples discussed illustrate very well how the extent of brain damage is determined by the concurrent dynamics of both harmful and protective processes engaging complex interactions between 

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