Emily Anthes is a science journalist and author. Her work has appeared in The New York Times, Wired, Scientific American, Psychology Today, BBC Future, SEED, Discover, Popular Science, Slate, The Boston Globe, and elsewhere. Read more
Misha Angrist is the author of Here is a Human Being: At the Dawn of Personal Genomics (HarperCollins), now out in paperback. He teaches at Duke University and blogs at blogs.plos.org/genomeboy.
Us…and Them
And after all we’re only ordinary men.
Roger Waters
As a graduate student, I studied the genetics of Hirschsprung disease, a congenital disorder of the nervous system in the gut (and, as I describe in my book, a disease that would affect my own family many years later). Among the things I found to be most gratifying (and yes, occasionally frustrating) in my doctoral studies were the interactions with Hirschsprung patients and families. We students had pledged our fealty to Science writ large, yes, but we weren’t studying roundworms or fruit flies. Our “subjects” (a descriptor of research participants that, in my opinion, is condescending and should be retired ASAP) were thinking feeling human beings. If we found a highly penetrant mutation in their DNA, it had the potential to alter their reproductive decisions and their lives. It meant something to them.
But even if it didn’t, shouldn’t life scientists-in-training, especially those whose model organism is Homo sapiens, have some sort of mandatory exposure to, you know, life? Should there not be some inevitable, meaningful exchange between researcher and researchee?
Denis Alexander is this week’s guest blogger. He has spent 40 years in the biological research community in various parts of the world, latterly as Head of the Laboratory of Lymphocyte Signalling and Development at The Babraham Institute, Cambridge which he left in 2008. Since then he has been heading up the new Faraday Institute for Science and Religion at St. Edmund’s College, Cambridge, where he is a fellow. Read more
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