Chimeric monkeys provide new disease model
Chimeric mice are one of the most important tools in biological research. By studying composite animals with tissues from distinct genetic lineages, scientists have gained important insights into the molecular mechanisms disease. This powerful biomedical research tool has largely been restricted to rodents and farm animals that are distantly related from humans, and, thus, might not best approximate human disease. Now, however, rhesus monkeys have joined the chimera club—an advance that researchers hope will help bridge the gap between mice and humans. “It is not enough to jump from mouse right to human in transplanting tissues,” says Shoukhrat Mitalipov, a … Read more
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