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Archive by tag | Hepatitis C

10 Apr 2014 | 10:00 EST

As gene therapy technologies blossom, ddRNAi tries to take root

Posted by Nicholette Zeliadt | Categories: Drugs, drugs and more drugs

As gene therapy technologies blossom, ddRNAi tries to take root

Before there was Twitter, there was Facebook, and before that, Friendster. And who can forget MySpace? There’s a similar trend of successive usurping technologies in the fast-moving quest to develop therapeutics capable of modifying the genome. Since the late nineties, we’ve witnessed the rise of several gene-silencing approaches, from “antisense” oligonucleotides and RNA interference (RNAi) to the latest targeted genome-editing techniques, such as those based on zinc finger nucleases or CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology. These rapid developments raise the stakes for companies that have wagered on a particular gene-silencing approach.  Read more

Tags:

  • Cancer
  • CRISPR
  • gene therapy
  • Hepatitis C
  • HIV
  • RNAi

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22 Oct 2012 | 09:00 EST

Prisoners, hard hit by hepatitis C, decry lack of access to drugs

Posted by Cassandra Willyard | Categories: Drugs, drugs and more drugs, Policy

Prisoners, hard hit by hepatitis C, decry lack of access to drugs

David Proulx was diagnosed with hepatitis C in 2003, but he suspects he contracted the virus decades earlier. He injected drugs in the 1970s and picked up several tattoos when he was first incarcerated in the early 1980s. Over the years, the infection wreaked havoc on his liver. Within a year of diagnosis, he received antiviral drugs to treat the disease, but the medicine failed to eliminate the virus. Proulx had run out of options. In 2011, however, the US Food and Drug Administration approved two new medications to treat hepatitis C. Clinical trials indicated that these drugs could help individuals like Proulx who had previously failed other therapies.  Read more

Tags:

  • Hepatitis C
  • Incivek
  • Victrelis

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