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Archive by tag | inflammation

26 Feb 2014 | 17:06 EDT

Promising psoriasis treatment signals hope for microRNA therapies

Posted by Nicholette Zeliadt | Categories: Drugs, drugs and more drugs

Promising psoriasis treatment signals hope for microRNA therapies

Nearly 2% of people worldwide chronically suffer from itchy and painful patches on their bodies, the manifestation of psoriasis, an incurable inflammatory disease in which immune cells infiltrate the skin and release molecules called cytokines that stimulate the skin cells to grow too rapidly. Treatments such as corticosteroids and immunosuppressants can help alleviate mild forms of the disease, and newer antibody-based therapies provide some relief for some of the most severe cases, but some patients fail to respond to these treatments or experience harmful side effects. Now, a new study shows that inhibiting a specific microRNA—a short bit of genetic material that influences the production of proteins in cells—appears to be an effective psoriasis treatment in mice, leaving researchers hopeful that this therapeutic approach will one day be tested in clinical trials.  Read more

Tags:

  • inflammation
  • microRNA
  • psoriasis
  • skin

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24 Feb 2014 | 17:00 EDT

Experimental diabetes drug reverses emphysema in mice

Posted by Nicholette Zeliadt | Categories: Diabetes and metabolism, Drugs, drugs and more drugs

Lung tissue damaged by emphysema

This year marks the 50th anniversary of the US Surgeon General’s first ever report, which implicated smoking as the primary cause of emphysema and other chronic diseases. Despite decades of research, emphysema—a form of chronic obstructive pulmonary disease (COPD), which ranks among the third leading cause of death in the US—remains incurable.  Read more

Tags:

  • COPD
  • diabetes
  • emphysema
  • inflammation
  • smoking

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