Nature Medicine | Spoonful of Medicine

Tale of two twins highlights role of chance in HIV infection

HIV is notoriously unpredictable. The virus can prove fatal rather quickly in some individuals, while it remains at bay in a rare group of people known as elite controllers. Doctors have puzzled as to why some patients can fend off the virus better with drugs, while others progress despite receiving the best antiviral medications available. A new study from a group led by Keith Crandall of Brigham Young University just south of Salt Lake City offers some explanation as to why HIV infection can produce such variable effects. Crandall’s team analyzed blood samples from a pair of identical twins who 


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