Nature Protocols | Stepwise

Modelling the molecules of life – a talk by Michael Levitt

Last night I went to an inspiring talk given by Michael Levitt, joint winner of the 2013 Nobel prize for chemistry. It was the 2014 Sir Ernst Chain Lecture at Imperial College, London. Starting with a project using lysozyme (where the co-ordinates for the computer input came from a ball and stick model and were typed onto punch cards) and early computer simulations of protein folding, to his more recent work on modelling ribosomes and eukaryote chaperonins, he presented a small slice of the amazing work that he and his collaborators have done. What was equally evident was the phenomenal advances in technology and computational power over the last 40 years. 

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