Top stories - Crestor: Risks Up, Risks Down
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Crestor: Risks Up, Risks Down
added on 11 Nov 2008
AstraZeneca took a pretty big risk in running a trial as big as the JUPITER one, but it seems to have paid off for them. As everyone has been reading, it appears that their Crestor (rosuvastatin), lowers the risk of cardiovascular events in patients with elevated C-reactive protein, even those wi...
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Crestor: Risks Up, Risks Down
posted to In the Pipeline on 22 Sep 2009
AstraZeneca took a pretty big risk in running a trial as big as the JUPITER one, but it seems to have paid off for them. As everyone has been reading, it appears that their Crestor (rosuvastatin), lowers the risk of cardiovascular events in patients with elevated C-reactive protein, even those wi...
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How Aggressive Should Doctors Be in Prescribing Statins After Jupiter?
posted to WSJ.com: Health Blog on 22 Sep 2009
The reduction in heart attacks in apparently healthy patients found in a study of AstraZeneca’s Crestor is a strong rationale for cholesterol-lowering statins to be used more broadly, some doctors say. But there are cardiologists, including the author of an editorial in the New England Jo...
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Should statins be put in the water?
posted to In The Field on 22 Sep 2009
The biggest story to come out of the American Heart Association’s annual jamboree is undoubtedly the JUPITER randomised controlled trial, which was showcased on Monday to a packed auditorium of over 6000 cardiologists. Data from the trial suggest that even healthy people with low cholesterol may ...
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Statins Are Better on JUPITER
posted to Science-Based Medicine on 22 Sep 2009
Over 26 million Americans are taking statin drugs. Some people think they should be available over-the-counter without a prescription, and it has even been facetiously suggested that they should be added to our drinking water. The protective effect of statins in cardiovascular disease and in high...
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Statins 'for everyone'
posted to NHS Choices: Behind the headlines on 22 Sep 2009
Taking cholesterol-lowering statin drugs could benefit millions, according to several high-profile stories in today’s papers. The Daily Mail’s front-page story claimed that a new “wonder drug” can dramatically cut the risk of heart attacks and strokes “for everyone”, even those without high chole...
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Crestor: Would It Save Any Lives?
posted to In the Pipeline on 22 Sep 2009
Should millions more people be taking Crestor? That’s a real balancing act. You have a decrease in heart attacks, but from a fairly small incidence rate. So at a minimum, you’ll need to balance the costs of those coronary events versus the cost of paying for all that Crestor. And statins are not ...
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Cardiologists circumspect on stellar JUPITER results
posted to In sickness and in health on 22 Sep 2009
The publication this week in New England Journal of Medicine of the JUPITER trial - which found that the statin rosuvastatin reduces the risk of heart attack and other cardiovascular events in people with normal cholesterol levels - has cause quite a stir. The likes of the BBC and the Daily Mail ...
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