The Niche

Cancer stem cell stories

Given the excitement generated bythe recent Nature Paper, here’s a list of cancer stem cell articles published by Nature Reports Stem Cells.

Also check out Nature’s web focus on cancer stem cells.

Cancer stem cells, becoming common

Tumour cells that can initiate a new tumour are not so rare as previously thought, putting the concept of the ‘cancer stem cell’ under the spotlight again.

Published online: 03 December 2008; doi:10.1038/stemcells.2008.153

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Two of a kind

Cancer stem cells use an embryonic stem cell-like transcriptional program to induce and maintain tumours

Published online: 11 September 2008; doi:10.1038/stemcells.2008.126

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Stem cell meeting 2008: in with the old, in with the new

Although excitement around advances in reprogramming somatic cells shows no signs of abating, new ideas regarding the field are surfacing.

Published online: 17 July 2008; doi:10.1038/stemcells.2008.108

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A mutant Methuselah for blood-making progenitors

Cells that regenerate blood increase tenfold in mutant mice

Published online: 24 April 2008; doi:10.1038/stemcells.2008.73

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Cancer and embryonic stem cells share genetic fingerprints

At least two modules of genes promote stemness

Published online: 17 April 2008; doi:10.1038/stemcells.2008.62

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Skin cancer needs beta-catenin

Without beta-catenin cancer stem cells no longer support tumours

Published online: 03 April 2008; doi:10.1038/stemcells.2008.57

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Cancer and stem cells: Beckman conference

Cancer cells emerge when checkpoints fail

Published online: 13 March 2008; doi:10.1038/stemcells.2008.47

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Stuck on youth

Some cancer stem cells retain an embryonic pathway

Published online: 24 January 2008; doi:10.1038/stemcells.2008.23

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MicroRNA reins in tumor-initiating cells

A microRNA that silences two oncogenes is quiet in cancer stem cells

Published online: 03 January 2008; doi:10.1038/stemcells.2007.137

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Leukemia might elbow out blood makers

A new mouse model helps researchers study human cancer cells

Published online: 01 November 2007; doi:10.1038/stemcells.2007.112

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Cancer stem cell sightings and slightings

Experts debate the rarity and relevance of ‘tumour-initiating cells’

Published online: 27 September 2007; doi:10.1038/stemcells.2007.93

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Stem cells not all to blame

Cells driving tumor growth may not be all that rare

Published online: 16 August 2007; doi:10.1038/stemcells.2007.75

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Stem cell meeting 2007: Routes and roadblocks on the way to cures

While the basic side of stem cell research is prospering, several talks on translating research to therapy were sobering reminders of the challenges ahead.

Published online: 12 July 2007; doi:10.1038/stemcells.2007.52

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What’s the relationship between stem cells and tumors?

Like some stem cells, cancer cells can grow without pause. Some cancers use stem cells’ tricks to do this, and so some cancer researchers study stem cells.

Published online: 14 June 2007; doi:10.1038/stemcells.2007.25

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The space race

Defective stem cells physically compete for space in the niche of the Drosophila ovary

Published online: 24 January 2008; doi:10.1038/stemcells.2008.24

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More reprogramming tips

A gene used to reprogram differentiated cells blocks microRNA processing

Published online: 06 March 2008; doi:10.1038/stemcells.2008.43

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Pituitary stem cells found using a general stem cell marker

Genetic approaches identify a distinct, postnatal stem cell population

Published online: 15 May 2008; doi:10.1038/stemcells.2008.77

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What comes after iPS?

Though applications of reprogrammed cells will be valuable, the questions they engender will be just as important

Published online: 03 April 2008; doi:10.1038/stemcells.2008.54

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