The Niche

Aging stem cells: trade-offs between vigor and cancer

Two papers from the University of Michigan show how tissue-specific stem cells trade regenerative potential to control unwanted proliferation. One, in fly testes from Yukiko Yamasita, shows that cells halt their division if the daughter cells would be misoriented. The other, in mice brains, shows how gene expression changes with age to favor decreased regeneration with decreased risk for tumorigenesis. 

BACK TO ARTICLE

Tell a Friend

Please ensure that your friend is content to receive an email from us with a link to the article. Select the following link to view our Privacy Policy.

BACK TO ARTICLE