For those of you who are looking to get started on your holiday shopping, I have the perfect suggestion. It's... the December issue of Nature Chemical Biology! It may not have the charm of that 100th tie or the universal appeal of old fruitcake, but it is jam-packed full of articles, reviews, perspectives, commentaries, and other goodies. This issue is actually a focus on drug discovery, so if the issue itself isn't enough, perhaps it will give you some ideas for other presents to buy for your loved ones. After all, who doesn't want some synthetic antibodies, treatments for parasitic diseases, or thoughts on new paradigms of drug discovery, whether they focus on academic-industrial partnerships or new ideas in integrating interdisciplinary techniques in general or in relation to cancer therapeutics? I could go on, but it's probably just easier if you check it out!

This issue is our first official focus, so we'd love to know what you think about it or other topics that we should cover. Happy holidays, everyone!

Catherine Goodman (assistant editor, Nature Chemical Biology)