« Reactions - Nicholas Long | Main | Chemist's choice »

NChem Research Highlights: Total synthesis, boron boride and sensor arrays

Action stations at Nature Chemistry HQ today...it's the deadline day for all the News and Views, Feature and other articles that make up the 'front-half' — the non-research articles — of the FIRST ISSUE. Exciting times.

This week, Steve gets to grips with more stereochemically odd natural products — not literally, as it might poison him — polychlorinated and 'stereochemically dense' chlorosulpholipids, a seafood toxin. The key step, an epoxide ring-opening, resulted in the wrong stereochemistry, suggesting an unusual intermediate.

You might have already seen the new form of boron that's been reported — after all, it's been in big Nature, the New York Times, the Conan O'Brien show and quite a swathe of blogs! But here's my take on the new form, including how it could be the first element with ionic bonding.

Being able to detect and identify proteins could help in diagnosing certain diseases, and many people are working towards sensor arrays that mimic how mammalian noses work (not sure I could smell the difference between too many proteins...). A new system has been developed that used quadruplexes of DNA arranged in a square. Each DNA strand has a fluorophore that gives off a different colour depending on which protein it's interacting with.

And finally...it's your last chance to enter our fabulous lab-coat picture competition! You can check out some of the entries (and our tea-pot cosy) on our Facebook group page.

Neil


Neil Withers (Associate Editor, Nature Chemistry)

TrackBack

TrackBack URL for this entry:
http://blogs.nature.com/cgi-bin/mt/mt-tb.cgi/7402

Post a comment

Comments will be reviewed by the editors before being published. You can be as critical or controversial as you like, but please don't get personal or offensive. We strongly encourage you to use your real, full name. Email addresses are required: this is in case we need to discuss your comment with you privately, or notify you in case we decide not publish your comment. Email addresses will not be made public on the blog.


Please enter the numbers you see below - this helps us to cut down on spam. If you are having trouble with this system, you can instead e-mail a comment to 'thescepticalchymist at boston dot nature dot com '.

Subscribe

Subscribe to this blog's feeds:

[What is this?]

Recent Comments

Out of 1046 total comments,
the most recent were:
Powered by
Movable Type 3.2