With the war on cancer well into its fortieth year, some scientists say its time to take a more forceful approach to beat the disease.

In recent years, researchers discovered that the growing tumor itself can push on the surrounding tissues triggering tumor invasion. Now, as described in a news story in the current issue of Nature Medicine, scientists are trying to understand these changes in the hopes of designing more effective therapies for the disease.

In this video slide show, find out how force is emerging to be critical to cancer metastasis.