ACS: Heroes…

I don’t attend too many press conferences at the ACS meeting – because they are aimed at a much more general audience than a chemistry journal editor (that’s not a bad thing – read on). On Sunday, however, I attended a press conference with the intriguing title of ‘New Heroes of Chemistry’. I really had no idea what this was about as I didn’t read the press release in advance.

From the ACS Portal:

Since 1996, the ACS Heroes of Chemistry program has recognized chemical scientists whose work in various fields of chemistry and chemical engineering has led to the successful innovation and development of commercial products based on chemistry. The Heroes of Chemistry program highlights the vital role of industrial chemical scientists and their companies in improving human welfare through successful commercial innovations and products. It presents an ideal opportunity to enhance the public image of the chemical and allied industries.

During the press conference, the ACS announced the induction of five new ‘Heroes of Chemistry’. Jotham Coe and Brian O’Neill (Pfizer) were involved in the development of a smoking cessation drug – Chantix (varenicline)– Joseph Armstrong III, Ann Weber and Nancy Thornberry (Merck) worked on a Diabetes drug – Januvia (sitagliptin).

The passion of these chemists for their work was clear to see – not least when Coe described how he had seen several close family members suffer and ultimately die from smoking related diseases. As we discussed in our September editorial, chemistry needs a few more champions (or heroes) and I really hope this kind of thing can help. And the best thing is that with this ‘hall of fame’ I don’t think there is any danger of the members later being accused of taking steroids to help get them there!

Incidentally, if you’re at the ACS meeting and want to read our September editorial – and the rest of the issue for that matter – why not pick up a complimentary copy from the expo (Booth 609).

Steve

Stephen Davey (Associate Editor, Nature Chemistry)

ACS: Heroes…

I don’t attend too many press conferences at the ACS meeting – because they are aimed at a much more general audience than a chemistry journal editor (that’s not a bad thing – read on). On Sunday, however, I attended a press conference with the intriguing title of ‘New Heroes of Chemistry’. I really had no idea what this was about as I didn’t read the press release in advance.

From the ACS Portal:

Since 1996, the ACS Heroes of Chemistry program has recognized chemical scientists whose work in various fields of chemistry and chemical engineering has led to the successful innovation and development of commercial products based on chemistry. The Heroes of Chemistry program highlights the vital role of industrial chemical scientists and their companies in improving human welfare through successful commercial innovations and products. It presents an ideal opportunity to enhance the public image of the chemical and allied industries.

During the press conference, the ACS announced the induction of five new ‘Heroes of Chemistry’. Jotham Coe and Brian O’Neill (Pfizer) were involved in the development of a smoking cessation drug – Chantix (varenicline)– Joseph Armstrong III, Ann Weber and Nancy Thornberry (Merck) worked on a Diabetes drug – Januvia (sitagliptin).

The passion of these chemists for their work was clear to see – not least when Coe described how he had seen several close family members suffer and ultimately die from smoking related diseases. As we discussed in our September editorial, chemistry needs a few more champions (or heroes) and I really hope this kind of thing can help. And the best thing is that with this ‘hall of fame’ I don’t think there is any danger of the members later being accused of taking steroids to help get them there!

Incidentally, if you’re at the ACS meeting and want to read our September editorial – and the rest of the issue for that matter – why not pick up a complimentary copy from the expo (Booth 609).

Steve

Stephen Davey (Associate Editor, Nature Chemistry)

Organic chemistry for the YouTube generation

Spoof music videos offer the chance for ageing chemistry geeks such as myself to relive both their chemical and musical past. This video in particular was the cause of much hilarity within the Nature Chemistry team. This video is great – although one of the early lyrics ‘in the lab, working alone’ is a cause for concern – so let’s hope that it is there for artistic reasons rather than anything else. But can such videos serve any useful purpose?

Well, this would be a fairly boring blog post if the answer was “No”, so I was delighted this weekend to hear from Neil Garg at UCLA about a small video project set as part of the sophomore organic chemistry course. For a small extra credit, Garg asked his class to make music videos highlighting aspects of the course.

No less than 140 out of 240 enrolled students took part and made a total of 61 videos – I’ll be interested to hear from Neil when the exam results are in! Although the videos are worth very little in the final score, it’s hard to believe that the students failed to learn something useful in the way of organic chemistry from making them.

Steve

Stephen Davey (Associate Editor, Nature Chemistry)

Organic chemistry for the YouTube generation

Spoof music videos offer the chance for ageing chemistry geeks such as myself to relive both their chemical and musical past. This video in particular was the cause of much hilarity within the Nature Chemistry team. This video is great – although one of the early lyrics ‘in the lab, working alone’ is a cause for concern – so let’s hope that it is there for artistic reasons rather than anything else. But can such videos serve any useful purpose?

Well, this would be a fairly boring blog post if the answer was “No”, so I was delighted this weekend to hear from Neil Garg at UCLA about a small video project set as part of the sophomore organic chemistry course. For a small extra credit, Garg asked his class to make music videos highlighting aspects of the course.

No less than 140 out of 240 enrolled students took part and made a total of 61 videos – I’ll be interested to hear from Neil when the exam results are in! Although the videos are worth very little in the final score, it’s hard to believe that the students failed to learn something useful in the way of organic chemistry from making them.

Steve

Stephen Davey (Associate Editor, Nature Chemistry)

Rhyming research

Great science is not easily recognized without good writing skills. In view of this, we have decided to introduce a new prerequisite for the consideration of manuscripts at Nature Chemistry: Authors are requested to include a short poem highlighting the novel conclusions of their work. (Special consideration will be given to those who prepare their entire manuscript in iambic pentameter.)

This new submission requirement will be in effect from the date of this blog post.

Steve

Stephen Davey (Associate Editor, Nature Chemistry)

Rhyming research

Great science is not easily recognized without good writing skills. In view of this, we have decided to introduce a new prerequisite for the consideration of manuscripts at Nature Chemistry: Authors are requested to include a short poem highlighting the novel conclusions of their work. (Special consideration will be given to those who prepare their entire manuscript in iambic pentameter.)

This new submission requirement will be in effect from the date of this blog post.

Steve

Stephen Davey (Associate Editor, Nature Chemistry)

A bit of a fischy answer

Readers in the UK will probably be aware of the TV quiz show ‘University Challenge’. It’s a general knowledge quiz in which teams representing universities and colleges from the UK compete (there’s no monetary reward, only the honour of winning). The questions asked are all pretty challenging, and it’s clear from watching the show that the question master — Jeremy Paxman — is extremely knowledgeable about…some of them. This is a fact that Neil has mentioned here before.

In my experience, chemistry rarely gets a good representation in the questions – the ‘chemistry’ questions have been known to include things like: ‘Name three of the four elements whose names spelt in British English end in ‘um’ but not ‘ium’. With a good 5–10 minutes to mentally work my way through the periodic table I could have done this (although there would never be enough time to do this on the show) but more importantly it doesn’t strike me as being about chemistry.

And hence to the point of this post: Paxman sometimes accepts answers slightly different than those on the question card – if he feels that the contestants have demonstrated that they have the right idea. Last night there were quite a few chemistry questions. Of particular note was a question asking for the type of compounds formed by the Fischer–Tropsch process. The answer on the card was hydrocarbons. The contestants were stumped. They nearly had it, but I would argue that their answer of ‘hydrogen and carbon’ wasn’t quite close enough. These two elements are not hydrocarbons. Paxman, however, awarded the points.

If we as chemists want people to understand what we do and why our jobs are important, then the subject needs to be represented more accurately in the mainstream media. Most chemists don’t learn to recite the periodic table, and don’t really care about how many elements end in ‘um’ and not ‘ium’— it has, after all, little to do with similarities in the respective elements reactivity.

I’m also not arguing that Jeremy Paxman should have known that the answer to the Fischer–Tropsch question was wrong. And I for one would love to see more questions like this included, but there needs to be guidance about what is a suitable alternative answer and what isn’t. Would he have been willing to award the points had the contestants offered a few real hydrocarbons such as propane and butane? I think this would be a far more valid answer, but I’d wager that it wouldn’t have done the contestants any good.

So here is a challenge for all of you. Can we come up with some questions that are really about chemistry, and that are:

1) Difficult (but not so tough that you wouldn’t have a chance of understanding them without a PhD in the topic area).

2) About things that you’d like a reasonably rounded individual — not necessarily a scientist — to have some idea of.

If you want you could even provide possible alternative answers that you think really are ‘close enough’.

I think the Fischer–Tropsch question would be about the right level – I’d be hard pressed to name a reaction you could consider more industrially important (there are of course a few that are equal)…

Steve

Stephen Davey (Associate Editor, Nature Chemistry)

A bit of a fischy answer

Readers in the UK will probably be aware of the TV quiz show ‘University Challenge’. It’s a general knowledge quiz in which teams representing universities and colleges from the UK compete (there’s no monetary reward, only the honour of winning). The questions asked are all pretty challenging, and it’s clear from watching the show that the question master — Jeremy Paxman — is extremely knowledgeable about…some of them. This is a fact that Neil has mentioned here before.

In my experience, chemistry rarely gets a good representation in the questions – the ‘chemistry’ questions have been known to include things like: ‘Name three of the four elements whose names spelt in British English end in ‘um’ but not ‘ium’. With a good 5–10 minutes to mentally work my way through the periodic table I could have done this (although there would never be enough time to do this on the show) but more importantly it doesn’t strike me as being about chemistry.

And hence to the point of this post: Paxman sometimes accepts answers slightly different than those on the question card – if he feels that the contestants have demonstrated that they have the right idea. Last night there were quite a few chemistry questions. Of particular note was a question asking for the type of compounds formed by the Fischer–Tropsch process. The answer on the card was hydrocarbons. The contestants were stumped. They nearly had it, but I would argue that their answer of ‘hydrogen and carbon’ wasn’t quite close enough. These two elements are not hydrocarbons. Paxman, however, awarded the points.

If we as chemists want people to understand what we do and why our jobs are important, then the subject needs to be represented more accurately in the mainstream media. Most chemists don’t learn to recite the periodic table, and don’t really care about how many elements end in ‘um’ and not ‘ium’— it has, after all, little to do with similarities in the respective elements reactivity.

I’m also not arguing that Jeremy Paxman should have known that the answer to the Fischer–Tropsch question was wrong. And I for one would love to see more questions like this included, but there needs to be guidance about what is a suitable alternative answer and what isn’t. Would he have been willing to award the points had the contestants offered a few real hydrocarbons such as propane and butane? I think this would be a far more valid answer, but I’d wager that it wouldn’t have done the contestants any good.

So here is a challenge for all of you. Can we come up with some questions that are really about chemistry, and that are:

1) Difficult (but not so tough that you wouldn’t have a chance of understanding them without a PhD in the topic area).

2) About things that you’d like a reasonably rounded individual — not necessarily a scientist — to have some idea of.

If you want you could even provide possible alternative answers that you think really are ‘close enough’.

I think the Fischer–Tropsch question would be about the right level – I’d be hard pressed to name a reaction you could consider more industrially important (there are of course a few that are equal)…

Steve

Stephen Davey (Associate Editor, Nature Chemistry)

ACS: Organic highlights

I’ve spent the majority of my time in the organic sessions here at the ACS meeting, and the standout highlights have to be the Young Academic Investigators on Monday and the Arthur C. Cope award scholars symposium yesterday. In the first of these I particularly enjoyed talks by Richmond Sarpong and Chris Vanderwal who both spoke on uses of pyridines in natural product synthesis – although from very different perspectives.

Richmond described synthetic efforts towards a number of heterocyclic products from a common bromomethoxypicoline; readers with a JACS subscription can read about it here. While the structure of the original pyridine is fairly well intact in Richmond’s final products, this could not be further from the truth for Chris who spends his time ripping pyridine rings open using the Zincke reaction, more details here.

Moving on to the Cope scholars, Paul Chirik‘s description of what he calls Modern Alchemy – essentially looking at how to use cheaper and abundant metals for catalysis was very entertaining. Apparently, if you need to explain to your mother why an iron catalyst might be better than a platinum one, then tell her that ’the price of stamps (self-adhesive) would increase by 5% per year because of the cost of platinum which can’t be recovered from the glue.’ Other highlights included Bill Jones dancing around the stage explaining the precession of a coordinated rhodium species around an aromatic ring, and Erik Sorensen’s description of the rapid construction of complex molecules such as the natural product (+)-FR182877

While looking up the last link, I couldn’t help noticing that Erik published this work with none other than Chris Vanderwal, and it leads me to this final thought: How many of the presenters in the young investigators session will appear in the Cope award scholars symposium at later ACS meetings and which future young investigators are they currently training?

Steve

Stephen Davey (Associate Editor, Nature Chemistry)

ACS: Organic highlights

I’ve spent the majority of my time in the organic sessions here at the ACS meeting, and the standout highlights have to be the Young Academic Investigators on Monday and the Arthur C. Cope award scholars symposium yesterday. In the first of these I particularly enjoyed talks by Richmond Sarpong and Chris Vanderwal who both spoke on uses of pyridines in natural product synthesis – although from very different perspectives.

Richmond described synthetic efforts towards a number of heterocyclic products from a common bromomethoxypicoline; readers with a JACS subscription can read about it here. While the structure of the original pyridine is fairly well intact in Richmond’s final products, this could not be further from the truth for Chris who spends his time ripping pyridine rings open using the Zincke reaction, more details here.

Moving on to the Cope scholars, Paul Chirik‘s description of what he calls Modern Alchemy – essentially looking at how to use cheaper and abundant metals for catalysis was very entertaining. Apparently, if you need to explain to your mother why an iron catalyst might be better than a platinum one, then tell her that ’the price of stamps (self-adhesive) would increase by 5% per year because of the cost of platinum which can’t be recovered from the glue.’ Other highlights included Bill Jones dancing around the stage explaining the precession of a coordinated rhodium species around an aromatic ring, and Erik Sorensen’s description of the rapid construction of complex molecules such as the natural product (+)-FR182877

While looking up the last link, I couldn’t help noticing that Erik published this work with none other than Chris Vanderwal, and it leads me to this final thought: How many of the presenters in the young investigators session will appear in the Cope award scholars symposium at later ACS meetings and which future young investigators are they currently training?

Steve

Stephen Davey (Associate Editor, Nature Chemistry)