Computational Research in Boston Seminar

Speaker: Robin Friedman (Massachusetts Institute of Technology)

Time: 12:30p-1:30p

Location: MIT Building 32-141

High-throughput Sequencing and Computation in

the search for a Gene Expression Code

The study of biology has historically been limited by a small set of slow and low-throughput tools. However, technological advances have led to an explosion in the amount of data available to biologists in the past few years. Almost overnight, computation has become an inextricable component of cutting- edge biology, especially in the field of gene expression, the study of how genetic sequence is translated into phenotypic effects. This talk will provide an overview of the impact of high-throughput sequencing on the study of gene expression from a computer science perspective. In particular, two examples will be presented: comparative genomics for microRNA binding sites and experimental quantification of transcription factor binding specificity.

Web site: https://math.mit.edu/crib

Open to: the general public

Cost: FREE

Sponsor(s): Mathematics, Department of

For more information, contact:

Alan Edelman

(617) 253-7770

edelman@math.mit.edu