Nature‘s latest Insight collection of reviews, Proteins to proteomes (Nature 450, 963-1009; 2007) is freely available online. Proteins are the most diverse and versatile set of biological macromolecules, having crucial roles in all biological processes. Now that whole complements of proteins (proteomes) for many cell types have been identified, we can begin to address the central question of how the innumerable protein functions are integrated so that a living cell interacts coherently with its environment. The Insight collection of five reviews covers vibrant areas of research in the ’protein world’, journeying from single-protein dynamics, to functional proteomics and drug discovery, via new technological developments in structural, computational, evolutionary and cellular biology.

The Insight supplement is available here.