The articles that have been downloaded most often, in PDF format, from the Nature website in July, are listed below and can be accessed online from this page. The chart does not rank the quality, scientific significance or citation impact of the content. However, it may bring articles to your attention that you might not have otherwise noticed. We hope you enjoy them.

Transvascular delivery of small interfering RNA to the central nervous system

Priti Kumar et al.

Nature 448, 39-43 (5 July 2007)

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

Marius Wernig et al.

Nature 448, 318-324 (19 July 2007)

Generation of germline-competent induced pluripotent stem cells

Keisuke Okita, Tomoko Ichisaka & Shinya Yamanaka

Nature 448, 313-317 (19 July 2007)

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Tarjei S. Mikkelsen et al.

Nature 448, 553-560 (2 August 2007) (published online 1 July)

Intronic microRNA precursors that bypass Drosha processing

J. Graham Ruby, Calvin H. Jan & David P. Bartel

Nature 448, 83-86 (5 July 2007)

Non-transcriptional control of DNA replication by c-Myc

David Dominguez-Sola et al.

Nature 448, 445-451 (26 July 2007)

Immunology: How a T cell sees sugar (News and Views)

D. Branch Moody

Nature 448, 36-37 (5 July 2007)

New cell lines from mouse epiblast share defining features with human embryonic stem cells

Paul J. Tesar et al.

Nature 448, 196-199 (12 July 2007)

Antitumour drugs impede DNA uncoiling by topoisomerase I

Daniel A. Koster, Komaraiah Palle, Elisa S. M. Bot, Mary-Ann Bjornsti & Nynke H. Dekker

Nature 448, 213-217 (12 July 2007)

Derivation of pluripotent epiblast stem cells from mammalian embryos

I. Gabrielle M. Brons et al.

Nature 448, 191-195 (12 July 2007)