The resurgence of interest in the underlying processes of metastasis has led to significant new insights and translational developments. Nature Reviews Cancer (9, 225; April 2009) presents a specially commissioned Focus on Migration and metastasis, in which all articles are free to access online for three months. The articles in the focus address new and emerging models and pathways that have been redefined with regard to their role in metastasis and metastasis suppression. From the journal’s Editorial:
“Metastases are the main cause of cancer-associated death and it seems surprising that there remain so many questions relating to the biology of metastasis. For example, how and why do metastases exhibit variations in tropism and latency? When are metastases seeded? What traits are required in tumour cells and the microenvironment to disseminate and seed a metastasis? How is one cell capable of so many sequential processes? And how might we predict and prevent or treat metastatic dissemination? Many of these questions are receiving renewed attention as new data provide insights into the biology of a metastatic tumour.”
Nature Reviews Cancer focus on migration and metastasis.
Nature Reviews Cancer web focus archive.
Nature Reviews Cancer journal homepage.
A guide to the journal: its content, policies and procedures.