The USCD-Nature Signaling Gateway would like to apply for continued funding from the US National Institutes of Health. If you are a researcher in this field, or if you are interested in this area and have been reading the articles and other content on the Gateway, please show your support by writing a letter to the team via this web form, before 30 May. Your response will help keep the content on the site freely available for all users.

The UCSD-Nature Signaling Gateway is a comprehensive and up-to-the-minute resource for anyone interested in signal transduction. The gateway represents a unique collaboration between the University of California San Diego (UCSD) and Nature Publishing Group, and is designed to facilitate navigation of the complex world of research into cellular signalling. Information and data presented here are freely available to all. It is powered by the San Diego Supercomputer Center (SDSC). It has won the Association of Learned and Professional Society Publishers (ALPSP) Award for Publishing Innovation for ‘a significantly innovative approach to any aspect of publication’.

The Signaling Gateway site has three main components: a data centre (repository and toolkits); Molecule Pages (structured data on key proteins); and Signaling Update (news and comment). The Signaling Gateway is an example of a pioneering business model that allows the scientific community free access to the wealth of cell signaling information through sponsorship, described in an article by Electronic Publishing Services as ‘the door to the future’