The Sunday Papers (23 April ’06 edition)

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Frigola et al.

Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band

Clark et al.

A distant upstream enhancer at the maize domestication gene tb1 has pleiotropic effects on plant and inflorescent architecture

Shore et al.

A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

Ueki et al.

Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes

Hashimoto et al.

Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass

Comments welcome.

One thought on “The Sunday Papers (23 April ’06 edition)”

  1. Graham, Kozyrev, Baechler, & Reddy et al.’s IRF5 and SLE paper is nothing short of a masterpiece in complex disease genetics. It details independant replication of an association of THE SAME DISEASE four times, together with reasonable functional data.

    Truly the gold standard in genetics. Certainly a target I admire, but what I shoot at in vain.

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