Arul Chinnaiyan kicked off the day for AACR’s 101st annual meeting in DC by talking about cancer genomes. He gave a roundup of some of the major genomes published to date, many of them in Nature. He even showed a brilliant screenshot of Heidi Ledford’s April 15 feature on the topic. Bert Vogelstein of Johns Hopkins followed up with a talk that seemed too good to be true, asserting that thanks to decades of research, cancer is essentially a known entity. He’s been comparing the genomic landscape of nearly 100 human cancer genomes that have been sequenced to date and other data to come up with 3142 genes that are mutated regularly.