The Society for the Study of Reproduction meeting in Kona, HI sports an eclectic mix of talks and posters — so eclectic, in fact, that I’ve regularly found myself asking just what many of the talks have to do with reproduction. The keynote address for example by Evan Simpson of Prince Henry’s Institute of Medical Research, Monash Medical Center in Australia covered his lab’s amazing work linking metabolic dysregulation, obesity, aging, and cancer. Nope, no reproduction there, except for the role of circulating androgens. Simpson laid out a career devoted to aromatase and the ways in which changes in estrogen signalling contribute to breast cancer. Fascinating stuff, but even he was a bit stymied by the link to cancer.