Nautilus
Poster on small RNAs from Nature Reviews Molecular and Cell Biology
Nature Reviews Molecular and Cell Biology presents a free poster on the productions and actions of small RNAs (ribonucleic acids), by V. Narry Kim and Mikiko C. Siomi. Recent progress in cloning, deep sequencing and bioinformatics have revealed an astounding landscape of small RNAs in eukaryotic cells. Small (20–30-nucleotide) RNAs, in association with Argonaute-family proteins, target messenger (m)RNAs and chromatin, and thereby keep both the genome and the transcriptome under extensive surveillance. The poster depicts our current understanding of the processing pathways of eukaryotic small RNAs and their possible mechanisms of action, and accompanies the Review article ‘Biogenesis of small RNAs in animals’ by V. Narry Kim, Jinju Han and Mikiko C. Siomi in the February issue of Nature Reviews Molecular and Cell Biology (10, 126-139; 2009).