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    Gilly Stoddart said:

    It is important to be clear that the ECHA statement does not mean that the two generation test will be replaced by one generation tests, because it is based on the assumption that registrants using the extended one generation test will breed to a second generation. This could mean that almost the same amount of animals will be used. The statement does acknowledge the possibility of using only one generation but while ECHA has unlocked the door to fewer animals being used in reproductive toxicity testing, it has not yet opened it. It is important that ECHA now recognises that Annex XI of REACH empowers registrants to avoid using two generations of animals for reproductive toxicity testing under weight-of-evidence provisions, but there are still bureaucratic – not scientific – obstacles in the way of companies seeking to use this method. REACH was designed to be flexible and this is a test case for that flexibility. The evidence is already clear that the extended one generation test is sufficient, as evidenced by OECD’s acceptance of TG 443. With this ECHA decision one more barrier has been overcome. We urge registrants to exploit this opportunity and urge the Commission and all member states to clear the remaining barriers as soon as possible, in the interests of both good ethics and good science. For more information about REACH and its effects on animal testing, please see (Dr Gilly Stoddart, Science Advisor, People for the Ethical Treatment of Animals)

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