The Seven Stones

E. coli counts in base 117

Finding general laws on the organization principle of living organisms is a particularly difficult task in biology but certainly a central one in systems biology. Part of the difficulty in this endeavor is probably linked to the fact that “by its very nature, life is both contingent and particular, each organism the product of eons of tinkering, of building on what had accumulated over the course of a particular evolutionary trajectory” (Keller, 2007, see also our post). Such laws are thus particularly significant when they emerge from evolutionary constraints alone. In a recent paper published in PNAS, Matthew Wright and colleagues may well provide such an example by looking at the “”″>chromosomal periodicity of evolutionarily conserved gene pairs” (Wright et al, 2007). 


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