{"id":979,"date":"2010-09-21T06:06:34","date_gmt":"2010-09-21T06:06:34","guid":{"rendered":"https:\/\/blogs.nature.com\/spoonful\/2010\/09\/lasker-awards-go-to-leptin-and-vegf-discoverers.html"},"modified":"2010-09-21T06:06:34","modified_gmt":"2010-09-21T06:06:34","slug":"lasker_awards_go_to_leptin_and","status":"publish","type":"post","link":"https:\/\/blogs.nature.com\/spoonful\/2010\/09\/lasker_awards_go_to_leptin_and.html","title":{"rendered":"Lasker Awards go to leptin and VEGF discoverers"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" alt=\"lasker.jpg\" src=\"https:\/\/blogs.nature.com\/spoonful\/files\/lasker-thumb.jpg\" width=\"200\" height=\"315\" align=\"right\" border=\"0\"><\/p>\n<p>Two researchers who discovered a hormone intimately linked to obesity and a scientist who found a protein associated to a common form of blindness have won this year\u2019s Lasker awards \u2014 the $250,000 prizes that often hint at future Nobel Prize recipients.<\/p>\n<p>Jackson Laboratory\u2019s <a href=\"https:\/\/www.jax.org\/news\/archives\/2005\/coleman_gairdner_award.html\">Douglas Coleman<\/a> and Rockefeller University\u2019s <a href=\"https:\/\/www.rockefeller.edu\/research\/faculty\/abstract.php?id=41\">Jeffrey Friedman<\/a> took home the Albert Lasker Basic Medical Research Award for co-discovering that the hormone leptin helps regulate appetite and body weight. In the 1970s, Coleman first showed that mice have some sort of appetite-suppressing substance in the blood, which Friedman later identified and called leptin, in 1994. (For a review by Friedman into therapeutic avenues of obesity research, click <a href=\"https:\/\/www.nature.com\/nm\/journal\/v10\/n6\/full\/nm0604-563.html\">here<\/a>.)<\/p>\n<p>This year\u2019s Lasker-DeBakey Clinical Medical Research Award was awarded to Genentech molecular biologist <a href=\"https:\/\/www.gene.com\/gene\/research\/sci-profiles\/rsrchonc\/tumbioangio\/ferrara\/\">Napoleone Ferrara<\/a>, who discovered how to block the protein <span class=\"caps\">VEGF<\/span> inhibitors to prevent vision loss in people suffering from wet macular degeneration. Roche-Genentech now markets a drug called Lucentis, which has been the focus on some <a href=\"https:\/\/www.nature.com\/nm\/journal\/v16\/n6\/full\/nm0610-611.html\">controversy<\/a>. (For a review by Ferrara into the <span class=\"caps\">VEGF<\/span> receptors, click <a href=\"https:\/\/www.nature.com\/nm\/journal\/v9\/n6\/full\/nm0603-669.html\">here<\/a>.)<\/p>\n<p><a href=\"https:\/\/www.imm.ox.ac.uk\/wimm-research\/molhaem\/sir-david-weatherall\">David Weatherall<\/a>, a retired medical geneticist from the University of Oxford, was also honored with the Lasker-Koshland Special Achievement Award in Medical Science for 50 years of \u201cinternational statesmanship in biomedical science,\u201d including discoveries into the genetic blood disorder thalassemia.<\/p>\n<p>To find out why the Lasker Awards are a lot like papal portraiture, check out this <a href=\"https:\/\/www.nature.com\/nm\/journal\/v15\/n10\/full\/nm1009-1137.html\">commentary<\/a> written last year by the chair of the Lasker Awards Jury, Joseph Goldstein.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Two researchers who discovered a hormone intimately linked to obesity and a scientist who found a protein associated to a common form of blindness have won this year\u2019s Lasker awards \u2014 the $250,000 prizes that often hint at future Nobel Prize recipients. Jackson Laboratory\u2019s Douglas Coleman and Rockefeller University\u2019s Jeffrey Friedman took home the Albert Lasker Basic Medical Research Award for co-discovering that the hormone leptin helps regulate appetite and body weight. In the 1970s, Coleman first showed that mice have some sort of appetite-suppressing substance in the blood, which Friedman later identified and called leptin, in 1994. (For a&nbsp; <a href=\"https:\/\/blogs.nature.com\/spoonful\/2010\/09\/lasker_awards_go_to_leptin_and.html#wpn-more-979\" class=\"more-link\"> &hellip; Read more<\/a> <a href=\"https:\/\/blogs.nature.com\/spoonful\/2010\/09\/lasker_awards_go_to_leptin_and.html\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":40,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-979","post","type-post","status-publish","format-standard","hentry","category-policy"],"_links":{"self":[{"href":"https:\/\/blogs.nature.com\/spoonful\/wp-json\/wp\/v2\/posts\/979","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nature.com\/spoonful\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nature.com\/spoonful\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nature.com\/spoonful\/wp-json\/wp\/v2\/users\/40"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nature.com\/spoonful\/wp-json\/wp\/v2\/comments?post=979"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nature.com\/spoonful\/wp-json\/wp\/v2\/posts\/979\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nature.com\/spoonful\/wp-json\/wp\/v2\/media?parent=979"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nature.com\/spoonful\/wp-json\/wp\/v2\/categories?post=979"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nature.com\/spoonful\/wp-json\/wp\/v2\/tags?post=979"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}