{"id":2379,"date":"2008-05-23T04:48:49","date_gmt":"2008-05-23T04:48:49","guid":{"rendered":"https:\/\/blogs.nature.com\/thescepticalchymist\/2008\/05\/nchem-research-highlights-silenes-cortistatin-and-magnetic-beads.html"},"modified":"2011-12-20T11:09:33","modified_gmt":"2011-12-20T11:09:33","slug":"nchem_research_highlights_sile","status":"publish","type":"post","link":"https:\/\/blogs.nature.com\/thescepticalchymist\/2008\/05\/nchem_research_highlights_sile.html","title":{"rendered":"NChem Research Highlights: silenes, cortistatin and magnetic beads"},"content":{"rendered":"<p>Morning everyone, it&#8217;s <a href=\"https:\/\/www.nature.com\/nchem\/archive\/categ_reshighlts_052008.html\">research highlight<\/a> time!<\/p>\n<p>Apart from having a really <a href=\"https:\/\/www.youtube.com\/watch?v=7z9bPrUark4\" target=\"_blank\">cheesy<\/a> headline(credit goes to Gav), my piece is on a double-whammy in <a href=\"https:\/\/www.nature.com\/nchem\/reshigh\/2008\/0508\/full\/nchem.15.html\">silicon chemistry<\/a>: the first compound with two C=Si double bonds <span class=\"caps\">AND<\/span> the first metal-substituted silene \u2014 in the same compound.<\/p>\n<p>Steve tackles some total synthesis, writing about <a href=\"https:\/\/www.scripps.edu\/chem\/baran\/html\/home.html\">Phil Baran<\/a>&#8216;s <a href=\"https:\/\/www.nature.com\/nchem\/reshigh\/2008\/0508\/full\/nchem.14.html\">assault<\/a> on (+)-cortistatin A, where they had to use a side door to access a ring-expanding cascade. There&#8217;s more about this over on <a href=\"https:\/\/totallysynthetic.com\/blog\/?p=996\">Totally Synthetic.<\/p>\n<p><\/a>And finally&#8230;how are your knees? If they&#8217;re suffering from osteoarthritis or acute pseudogout, chances are they&#8217;ve got crystals of calcium phosphate in them. Read Gav&#8217;s <a href=\"https:\/\/www.nature.com\/nchem\/reshigh\/2008\/0508\/full\/nchem.13.html\">highlight<\/a> about how the crystal culprits can be detected with magnetic beads.<\/p>\n<p>Neil<\/p>\n<p>Neil Withers (Associate Editor, <a href=\"https:\/\/www.nature.com\/nchem\"><em>Nature Chemistry<\/em><\/a>)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Morning everyone, it\u2019s research highlight time!&nbsp; <a href=\"https:\/\/blogs.nature.com\/thescepticalchymist\/2008\/05\/nchem_research_highlights_sile.html#wpn-more-2379\" class=\"more-link\">Read more<\/a> <a href=\"https:\/\/blogs.nature.com\/thescepticalchymist\/2008\/05\/nchem_research_highlights_sile.html\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":122,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20,22],"tags":[],"class_list":["post-2379","post","type-post","status-publish","format-standard","hentry","category-nchem-research-highlights","category-neil-withers"],"_links":{"self":[{"href":"https:\/\/blogs.nature.com\/thescepticalchymist\/wp-json\/wp\/v2\/posts\/2379","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nature.com\/thescepticalchymist\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nature.com\/thescepticalchymist\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nature.com\/thescepticalchymist\/wp-json\/wp\/v2\/users\/122"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nature.com\/thescepticalchymist\/wp-json\/wp\/v2\/comments?post=2379"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nature.com\/thescepticalchymist\/wp-json\/wp\/v2\/posts\/2379\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nature.com\/thescepticalchymist\/wp-json\/wp\/v2\/media?parent=2379"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nature.com\/thescepticalchymist\/wp-json\/wp\/v2\/categories?post=2379"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nature.com\/thescepticalchymist\/wp-json\/wp\/v2\/tags?post=2379"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}