A free poster, by Matthias P. Wymann, Thomas Rückle, Christian Rommel, Matthias Schwarz and Roger Schneiterfrom, is published this month (February) by Nature Reviews Molecular Cell Biology . The poster provides an overview of the protein—lipid signalling network, and how this network can be exploited pharmacologically in the study of proliferative, inflammatory and metabolic diseases. It accompanies a review article by Matthias P. Wymann and Roger Schneiter in Nature Reviews Molecular and Cell Biology (9, 162-176; 2008), which also contains a Web Focus on Lipids.