Pushing the Reset Button for Vernalization

the resetting mutant

Recent years have witnessed great advance in our mechanistic understanding of vernalization in overwintering plants. The FLC locus, the hub of vernalization network, is epigenetically silenced by polycomb-mediated histone methylation during vernalization, which thereby removes the suppression on the FT locus for flowering to occur. We know that during embryogenesis this histone methylation of FLC is reset to ensure a requirement for vernalization in each generation but little is known about the resetting mechanism.  Read more