The latest Nature Insight (460, 813-862; 2009 – free to access online for six months from publication date) is on metalloproteins — proteins containing metal atoms or clusters — which are involved in a wide range of important biological processes. The articles in this Insight review recent advances in our understanding of metalloproteins, including how enzymes containing complex metal clusters metabolize small gaseous molecules, how proteins containing iron–sulphur clusters are assembled, and how enzymes containing a single metal ion catalyse the halogenation of small organic molecules. This Nature Insight is accompanied by a special podcast on metalloproteins, which features interviews with several of the authors.

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