Scientific Data is inviting submissions releasing and describing data from high-throughput screens employing cutting-edge 3D cell or tissue culture systems. Screens using a wide range of perturbations will be considered, including chemical libraries or functional genomic screens. Priority will be given to submissions that employ high-content imaging techniques, and which have particular value for methods development in this growing area. Read more
Scientific Data is inviting submissions that provide compelling examples of how portable computing technologies can be used to create transparent, reproducible descriptions of data processing workflows. Submissions considered for this collection should describe valuable research datasets that involve some form of computational processing in their production. Authors should provide source code for all data processing steps in a way that would allow others, including referees, to easily understand and execute all processing steps. Read more
Scientific Data is inviting submissions that release and describe datasets from studies that employed multiple ‘omic’ profiling technologies, including, but not limited to, genomics, epigenomics, transcriptomics, proteomics and metabolomics. Submitted articles may be considered for inclusion in a special article collection to be published at the journal. Read more
Today, we are releasing a new checklist for authors drafting Data Descriptors that build or expand on other publications. It is now available on our Editorial & Publishing Policies page and from the link below. Read more
Early on in her behavioural observations of the chimpanzees at what is now known as Gombe National Park, Jane Goodall was struck by their personalities, which were as distinct as our own1. However, upon sharing her observations with a ‘respected ethologist’, she was told that, yes, animals differed in their behaviour, but that this was best ‘swept under the carpet’ (pp 11-12)2. Read more
Today, we released a thoroughly revised and improved version of our Submission Guidelines, making submitting to Scientific Data easier than ever before. Read more
Huntington’s disease (HD) is a fatal neurodegenerative disorder caused by a mutation in the huntingtin gene1. The progressive break down of brain neuronal cells in HD patients leads to deteriorating mental and physical abilities over a 10-20 year period prior to death, the symptoms often described as having Parkinson’s disease, Alzheimer’s disease and amyotrophic lateral sclerosis (ALS) simultaneously2. At the start of the huntingtin gene there is a CAG trinucleotide repeat region that encodes a stretch of poly-glutamine residues in the amino-terminus of the encoded protein. This repeat tract is expanded in HD patients. The repeat length of this region correlates with the age of symptom onset3. Affecting approximately 1 in 10,000 of the population4, rare juvenile forms of the disease exist in patients with the longest CAG expansions, although adult-onset HD patients typically have between 40-50 CAG repeats with symptom onset beginning between the ages of 35-50. Read more
Manuscripts published at Scientific Data contain a ‘Data Citations’ section that helps authors formally acknowledge any datasets mentioned in their manuscript. We know that this section is unfamiliar to many of our authors, so here we provide some background on the purpose of data citations, and advice on completing this section when submitting to Scientific Data. Read more
Blog from Mathias Astell and Iain Hrynaszkiewicz on the difficulties in sharing non-public clinical data and a set guidelines being developed by Scientific Data to help researchers, repositories and journal editors best provide access to, and awareness of, clinical data.
Scientific Data is an online-only, peer-reviewed publication for descriptions of scientifically valuable datasets. Follow this blog for news about Scientific Data, as well as commentary from our editors and the diverse set of researchers, funders, and data managers who are supporting us. Find out more