Researchers at MGH, Children’s: Love my boss, co-workers; hate my job

We notice that Children’s Hospital is tweeting its own horn about coming in as No. 7 in a ranking of the best academic institutions for researchers to work. According to a survey by The Scientist trade newspaper, Children’s came in right after The Trudeau Institute of Sarnac Lake, New York.

(As the accompanying article put it, “among the winners of this year’s survey are few places that don’t automatically spring to mind as hot beds of research.”)

We don’t see any other tweets from Boston area hospitals, probably because only one other — Mass General — made the top 40 list. Maybe the folks over there thought coming in at No. 29 was nothing to chirp about.

Oddly, respondents listed “job satisfaction” as a weakness at both institutions. So, it’s clear best doesn’t mean most satisfying in this case. “Tenure and promotion,” which were also listed as weaknesses must not factor in. The survey found that “peers” and “management and policies” were cited as strong points at both institutions.

Click here to read about the methodology, which included a web survey and email to Scientist readers. The results were based on about 2,300 responses.

Research needed to make farming sustainable

Agricultural research needs to focus more on making farming sustainable, including looking at its effects on water use and the social and economic impacts on farmers lives, and not just on increasing food production, a report recommends.

The report from the National Academies’ National Research Council published yesterday says federal and state agricultural R&D programmes should “aggressively” fund research on sustainable farming practices, such as crop rotation and integrated livestock and crop production, to ensure future food demands are met.

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Do you take honey with your toxins?

MB Jarrosak cropped.JPGBees may seem a surprising choice as a monitoring tool. But their sensitivity to chemicals has made some scientists big fans.

The buzzing, pollen-loving insects have been utilised for potential bomb detectors at airport, landmine seekers, and pollution monitors.

Using living organisms to test environmental health is known as bio-monitoring, and it dates back to the classic canary-in-a-coal-mine trick. Now the New York Times has a nice story on how the Düsseldorf International Airport and seven other airports are using bees to monitor air quality.

If plants have been exposed to toxins, that would show up in the nectar and any subsequent honey from bees that visit the flowers. By keeping hives near an airport, you should have a natural accumulator of any pollutants.

The first batch of this year’s honey harvest from some 200,000 airport bees was tested in early June, and indicated that substances such as certain hydrocarbons and heavy metals were far below official limits.

Local bee-keepers keep the bees, bottling up the honey – Düsseldorf Natural – which was comparable to honey produced in areas without any industrial activity and can be gifted, reports the Times.

Image: photo by MB Jarrosak via Flickr under creative commons.

Yucca Mountain nuclear project will not die

yucca.jpgAmerica’s two-decade old proposal to store high level nuclear waste in a mountain in Nevada just will not die.

Geologists, local senators, and President Barack Obama have all tried to kybosh plans to build a waste storage facility inside Yucca Mountain.

But yesterday three judges from the Atomic Safety and Licensing Board, part of the Nuclear Regulatory Commission (NRC), ruled that Obama doesn’t have the power to kill the Yucca dream. He cannot overrule the act passed by Congress in 1982 that specified the mountain as the resting place for waste from nuclear power plants across America, they said.

When the Department of Energy (DoE) tried to withdraw the 8,600-page construction authorization detailing the Yucca plans various states and other groups objected. Now the judges have denied the application to withdraw.

“Did Congress, which so carefully preserved ultimate control over the multi-stage process that it crafted, intend – without ever saying so – that DoE could unilaterally withdraw the Application and prevent the NRC from considering it? We think not,” they wrote (verdict, hosted by NY Times).

A spokeswoman for the DoE insisted that the agency did have the legal authority to withdraw the application and was confident the judges’ decision would be overturned by the Nuclear Regulatory Commission (NY Times, AP).

The fight looks set to continue.

Senator Patty Murray, from Washington State – one of those opposed to the application, says, “Given today’s decision, the Department should stop all current actions to terminate the project. Over the last 30 years, Congress, independent studies, and previous administrations have all pointed to, voted for, and funded Yucca Mountain as the nation’s best option for a nuclear repository.”

On the other side, Harry Reid, one of Nevada’s senators, says, “Nevadans can rest assured that as the majority leader of the Senate, I will continue working with President Obama and Secretary Chu to ensure Nevada never becomes the nation’s nuclear dumping ground. I will continue to ensure that this dangerous project never comes back to life.”

So there may, in fact, be a simple solution to the long term storage problem: by the time the wrangling over Yucca Mountain has stopped, the waste probably won’t be radioactive any more. It’ll only take a million years or so.

Image: former secretary of energy Spencer Abraham with the 2002 recommendation that Yucca Mountain becomes America’s long term waste store / DOE Photo

Lindau Roundup: Sessions From Monday And Tuesday

We’re on Day 3 of the Lindau Conference, the annual gathering of Nobel laureates and junior scientists. Despite a crammed schedule, with a staggering 20 sessions on the first day alone, several attendees have nevertheless found time to share their experiences on the official Lindau blog.

Monday

Martin Fenner kicks things off, with a discussion on the second session of the day, in which Jack Szostak discusses artificial cells. Alexander Bastidas then leaps to the opposite extreme of scale, with notes on a talk by John Mather on the history and future of the Universe.

Monday’s late morning sessions were dominated by medical research. Jessicca Ricco presents a neat summary of the talks, including Harald zur Hausen on the links between infections and cancer and Francoise Barré-Sinoussi on the discovery of HIV and the importance of global translational research to counter it.

Ashutosh Jogalekar discusses the work of laureate and afternoon speaker Paul Crutzen, who shared the 1995 Chemistry prize for his work on CFCs and ozone depletion. Ashutosh talks at length about Crutzen’s more recent work on geoengineering.

Akshat Rathi also summarises Monday’s lectures, before describing the formal meal in the evening.

Tuesday

Martin Fenner speaks to GFP pioneer Roger Tsien, who started the day with a session on designing nanoparticles to treat disease. We learn that “visually beautiful research results are the best motivation, and that winning a Nobel Prize doesn’t mean that papers and grants come easily.”

Martin also recounts a morning panel discussion between laureates entitled Impact of Chemistry and Physics to Biomedicine. Where is the Future? His partial transcript focuses on questions from young researchers. Alexander Bastida also covers this panel discussion from a neuroscience perspective.

And finally, Lou Woodley does a quick analysis of some of the most entertaining talks from Monday and Tuesday morning, looking at the personalities, puns and pictures in the plenaries.


As if the programme isn’t enough to make you jealous, Lou aslo shares a few photos of the beautiful surroundings of Lindau. Xian Gao also contributes a few snaps over on the Nature China at Lindau blog.

You can also watch the first video diaries from the roving team of young scientists, courtesy of Beatrice Lugger, who also captures some post-lecture dancing.

Science Museum Lates Tonight!

Who’d ever have believed people would queue for science? But queue-they-do for the monthly Lates evening at the Science Museum. Tonight’s event will be no exception as curious adults wait in line for a chance to tour the museum’s treasures with live music, wine and NO CHILDREN.

This month’s theme matches up to the venue’s new gallery, which focuses on genetics, neurobiology and how these lead to our sense of identity. (Keep an eye out for a table full of knitted people – members of Stitch London, including my wife, have crafted woollen versions of themselves for the exhibition.)

Expect games, quizzes, voice-altering gizmos, face-morphing gadgets, few tourists and, did I say it already?, NO KIDS. The fun and games start at 6.45pm and last till 10pm. Entrance is free.

Cloud computing in biology

The sheer amount of data being generated in large-scale high-throughput biological studies is challenging current capabilities for data storage and analysis. One solution to this has been to move to cloud computing. In our editorial this month we discuss current efforts in this direction and the particular challenges of biological analysis in the cloud.

Annals statin dust-up gets personal

Just a few years ago, researchers rarely identified industry sponsors of their clinical trials.

But when these conflicts of interest began to emerge, so did questions of bias. Now, as one critic puts it, we have “an orgy of disclosure.”

So, it was a bit surprising to see the reaction to a piece in last week’s issue of the

Annals of Internal Medicine suggesting corporate sponsorship may have introduced bias in the Jupiter study., That study concluded that statins are effective for primary prevention of heart attacks in patients with normal cholesterol but high CRP levels.

In a story in The Heart Wire on the flap, PI Paul Ridker of Brigham and Women’s Hospital notes that his corporate sponsorship is well known and that BWH owns the patent for the CRP test in question.

This is one of the most independent trials ever done. We had a truly independent DSMB, totally independent statisticians, and we structured this trial to be completely independent of the company.’

He also charged critics with “going after” Rory Collins, who chaired the data monitoring committee.

In the same story, Dr Steven Nissen of the Cleveland Clinic stood up for Ridker and Collins, calling the critical AIM paper “troubling and, frankly, offensive…” The authors, he said “spend much of their paper impugning the integrity” of Ridker and Collins.

Another website, CardioBrief, described two of the paper’s authors as member of “obscure, cult-like group of cholesterol skeptics.”

So, NNB checked in with the local author on the paper, John Abramson. He is not a member of the “cult” but is a clinical instructor at Harvard Medical School and the author of the 2008 Book Overdosed America.

He said no one should take personal offense when researchers raise questions about conflicts of interest.

I think it’s a smoke screen to cover up the real issue in the article that we wrote in the AIM, which is that the numbers that were reported in the NEJM don’t add up.

He believes an independent analysis of all of the data would answer many of the questions he and his group raise. But, that data is not available.

Data from commercially sponsored trials is treated as proprietary information, like the recipe for Coke. … That’s a major problem. .. Even though this data is privately owned, it functions as a public good in society. It is going to command public funds and it is going to dictate how people are treated. .. This trial is so important that the researchers and the sponsors, in good faith, ought to open up the data to independent analysis. I don’t mean just the calculated data— I mean the case reports from the individuals who had adverse events in the study. It’s like having a corporate financial report that the corporation doesn’t allow to be audited independently

He also notes that he’s not a member of the cholesterol skeptics group like his co-authors and believes that statins are useful.

I think people who have heart disease benefit from taking a statins… Statins also appear to benefit very high risk men who don’t have heart disease…… They certainly can’t paint all of us with the same brush.

Can Cancun or Cape Town cap Copenhagen?

bodansky.jpgSix months after UN climate talks splintered in Copenhagen, pundits are still chewing over what went wrong. Do future UN meetings, in Cancun this December and in Cape Town in 2011, have any chance of rescuing a global deal in which countries will agree to set meaningful limits on their emissions? If not, where do we go from here?

Speaking on Sunday at the Smith School’s World Forum on Enterprise and the Environment in Oxford, UK, Dan Bodansky (pictured), an expert in climate change law, asserted that the troubles in Copenhagen were not down to dysfunctional negotiations during the conference. Instead, the problem lay with basic political disagreements that had not changed before or after the meeting. Apart from the differences of position between developed and developing countries, the US and China are both fundamentally unwilling to sign up to binding international commitments, he noted. “I am sceptical that these meetings will do better in the future,” he said.

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