Academia to industry and back again

Eric Betzig, one of three chemistry Nobel laureates from 2014, shares what he learned from working in both academia and industry, and how he applies it to his career now.


Naturejobs-podcast
It’s often said that being a science graduate is a great thing: it opens so many doors and gives you the chance to take on any career. Although this might be true, it also makes deciding what career to focus on, and train for, very difficult.

This month, Nature Careers published a great piece based on the 2015 Nature Graduate Student Survey, where Nature tried to uncover what careers early career researchers were hoping to get, and how they were preparing themselves. In this podcast I was joined by Monya Baker, one of the Nature Careers editors, to give us some further insight into the survey.

The second part of the podcast is an interview I did with Eric Betzig, one of the three chemistry Nobel prize winners in 2014. In our chat we talk about his work in breaking the diffraction limit, what it’s like to see living cells move and his transitions from academia to industry and back again.

Lessons from a laureate

Carina Dehner shares what she learnt at the 2015 Lindau Nobel meeting from Professor Peter Doherty, winner of the Medicine or Physiology Nobel in 1996.

Guest contributor Carina Dehner

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The Nobel Prize is a highly coveted and uniformly respected accolade. Receiving this honor opens almost every single door in the world; seemingly every country will welcome you with open arms. For example, the American immigration system will immediately provide you with a green card–. Furthermore, it conveys life-long prestige which many use to influence policy.

But, what is so special about these laureates? What happened in their lives and education that primed them for their seminal achievements? At the 2015 Lindau Nobel meeting I had the opportunity to interact with Professor Peter C. Doherty, winner of the 1996 Medicine or Physiology Nobel for his research on the immune system. He and Rolf Zinkernagl discovered how the immune system recognizes cells infected by a virus, deepening the understanding of how the immune system distinguishes self from foreign molecules. I was interested in his work as it closely relates to my own research on autoimmune diseases. What I was most excited about, however, was what I could learn from someone who has reached what many consider to be the pinnacle of a scientific career.

Nonlinear paths

Doherty began in Australia as a veterinary doctor, then switched to pathology, where he made his novel findings in immunology research. This meandering path is not unique to Doherty – many scientists often switch research fields, following research questions they find interesting. This type of career path is worth considering because it might stop you from developing tunnel vision and be open for other aspects.

Mentors

Today young scientists are advised to seek a mentor, but it struck me as interesting that Doherty’s never had one. Although he did mention annual meetings with a supervisor in pathology, he never gleaned constructive feedback that helped guide and formulate his thinking. He often left meetings with a simple “good idea” and nothing more. But this obviously did not discourage him.

He doesn’t believe mentors are the be-all-and-end-all. Many senior scientists are extremely busy, and might not be able to focus much attention on your needs as a young researcher. Instead, he suggests speaking to those who are just one or two steps ahead of you in your chosen career path to find out what they’ve experienced. Not only that, but if you want the best learning experience, “it helps to have a mentor who will continue to be enthusiastic about you after you’ve left “the fold”.

Yet he does his best to help his current students. Now, Doherty spends more time away from the bench, reviewing his staff’s papers and working with them to improve their communication skills. “Being able to express him- or herself is one of the most important things in a scientist,” he says.

Science communication

As part of my experience at Lindau, I was given the opportunity to present my research in Doherty’s master class on immunology research. I learned how difficult it can be to convey one’s research to an audience, particularly those not in your field. In asking essential word definitions and mechanisms in immunology – addressed to the audience, he made it obvious how important it is to make one’s own work understandable for any audience. Instead of skipping the details he recommended focusing on the message of the project.

Doherty enjoys communicating ideas that are important to him and encourages young scientists to express their opinions, thoughts and most importantly their work to others. One way he recommends is by submitting written articles to publications like The Conversation. “[It] is a great option for spreading your work – it’s openly accessible and it saves you from wrong journalism – you yourself can set your point of view there,” he says. He believes that the problem lies with well-qualified science journalists losing their jobs, “and the fact that media organizations push a particular (and at times toxic) line.”

So instead he suggests scientists reach out to the public themselves. “The lack of awareness of science and how it works is dangerous, especially when ignorance is a license to deny realities that may be dangerous to us,” he says. “We need everyone to speak up, and younger people are more likely to be adept in the ‘new media’.”

His advice on how to learn to do this is to just get writing.If you can find someone who is good and will read your stuff, listen to what they tell you,” he says. He had a short list of tips that would be useful for any scientists, whatever their career stage:

Less is more. You don’t have to cover everything. Instead, focus on getting a key message across.

Tell a story, whatever format you use.

Avoid jargon where you can.

Don’t reproduce anything you don’t understand. “If you read an impressive argument or statement that you don’t understand, don’t reproduce it. The originator probably doesn’t understand it either!”

The end goal

When reflecting on the Nobel itself, Doherty believes that “this prize is much more recognition than what you deserve – suddenly things come up you never thought about before.” But there are also advantages of a prize like this. He now has the ability to provide yearly financial support for the training of young scientists, which brings him much joy.

Mentoring: Where laureates go for advice

Mentorship advice comes in many forms and from many sources, say Nobel laureates.

Contributor Michael Gatchell

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Mentors are fundamental in molding young scientists into independent researchers. These relationships can take on many forms and evolve along the way, but they never stop being important for a scientist.

Relationships with mentors change as a young scientist’s career progresses and they gain experience. But it is naïve to think that you are less dependent on the advice from your peers as you grow. “I think you need more advice in a way, but different types,” says Martin Chalfie, 2008 Nobel laureate in chemistry. Venkatraman Ramakrishnan, 2009 Nobel laureate in chemistry, agrees that it is important to have somebody who you trust to discuss major decisions with. He maintained a close relationship with his postdoctoral mentor as his career progressed, “He was always very honest — I didn’t always agree with him — but I always found it useful to talk to him.” Continue reading

Mentoring: Before they were laureates

Mentors create environments where early career researchers can grow and develop.

Contributor Michael Gatchell

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For a young scientist the possibilities are endless, but a good mentor can make all of the difference in helping their career off to the right start.

Those who choose to become scientists can often point out one or several people who influenced them and started them on the journey that is their career. Already at an early stage in one’s education, there can be that one professor who made a longstanding impact. Even seemingly small actions make a big difference. This was the case for 2008 Nobel laureate in chemistry, Martin Chalfie. He fondly remembers a special teacher while he was an undergraduate student at Harvard, who personally ensured that Chalfie had a key to the library and could read the papers needed for a course. “He went out of his way — that was a wonderful thing,” Chalfie says.

The first experience that many people have of actually practicing science is during graduate school. The advisors naturally take on the role as mentors and create an environment where they can grow. This can be manifested in many different ways. For Brian Schmidt, winner of the 2011 Nobel Prize in physics, having frequent meetings with his PhD supervisor at Harvard were important. “Every morning I would bring in a plot of what I did the day before and we would talk it over,” he says. “He really imprinted lots of how to do science to me.” Continue reading

Mentoring: The perspective of Nobel Laureates

The first of a three-part series on the mentoring experiences from Nobel Laureates.

Contributor Michael Gatchell

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One group of people that have experienced the greatest thrills science has to offer has to be the Nobel laureates.

Science is about discovering and understanding the unknown. To do this you need an open mind and follow paths that no one else has walked down before. The classes you take as a student and books you read provide the basic knowledge, but it is the interactions with people around you that mold you into a true scientist — ready to take on the greatest problems that nature has in store.

Every Laureate has a unique story of making choices along a nonlinear career path. But as any of them will tell you, it is important to have an ensemble of mentors that you trust for advice at any point along the way, not only when you are young and inexperienced. “You cannot learn science from books — you have to learn science from other people, who give you the right imprint,” says Carlo Rubbia, 1984 Nobel Laureate in physics. Continue reading