If you were given a choice between a large protein-protein interaction data set obtained by high-throughput experiments and another data set extracted from a collection of small-scale experiments via literature mining, which one would you trust more?
A Correspondence in the May issue of Nature Methods points to the fact that the widely used human cytomegalovirus promoter shows dramatic differences of expression in various cell types.
The Correspondence focuses on potential problems associated with CMV in the brain in relation to a paper by Wickersham and Callaway who respond to the criticism.
Share your experience with CMV in neurons or other cell types by adding your voice to the discussion.